Publications by authors named "V B Oza"
Background: Binimetinib and selumetinib are two mitogen-activated protein kinase kinase (MEK) inhibitors used to treat low-grade gliomas and plexiform neurofibromas. Cutaneous toxicities are commonly associated with MEK inhibitors; however, limited studies have examined cutaneous effects in a pediatric population or whether toxicities vary between MEK inhibitors.
Methods: We conducted an IRB-approved, single-center, retrospective review of pediatric neuro-oncology patients on binimetinib or selumetinib who presented to NYU from April 2016 through July 2022.
Article Synopsis
- - The study investigates the effectiveness of endoscopic ultrasound (EUS)-guided celiac plexus block versus a sham procedure in alleviating abdominal pain for patients suffering from chronic pancreatitis, with the aim of determining pain reduction statistics.
- - Conducted as a randomized sham-controlled trial, the research will involve multiple academic sites and focus on patients whose chronic pancreatitis is confirmed by EUS diagnostic criteria, measuring outcomes like pain reduction through specific pain assessment tools.
- - The ultimate goal is to provide a clear evaluation of celiac plexus block’s efficacy compared to a placebo treatment, which may help in managing chronic pain related to pancreatitis more effectively.
Article Synopsis
- Treatment of anastomotic ulcers, which are difficult to manage, often fails with standard methods.
- PuraStat, a synthetic peptide gel, is used for stopping bleeding in the digestive tract and has potential benefits for these ulcers.
- In a study involving multiple centers, 9 out of 10 patients treated with PuraStat alongside regular therapies showed improvement, suggesting it can help heal these ulcers effectively.
Article Synopsis
- - Wound management involves various techniques and materials to help heal both acute and chronic wounds, focusing on successful wound closure and preparing for surgical options when necessary.
- - Dressings should promote healing while reducing fluid loss, pain, and infection; nanotechnology has been a game-changer by enhancing dressings with better strength and targeted drug delivery.
- - Recent innovations like smart materials and personalized therapeutics are advancing wound care, aiming to improve healing speed and reduce scarring, ultimately shifting towards a patient-centered approach.