[The levels of cortisol and glycosaminoglycans in patients with uveitis in rheumatic diseases].

The serum levels of cortisol and glycosaminoglycans (GAG) were studied in patients with uveitis in rheumatic diseases (RD). Among the patients with this pathology, there was a more preponderance of persons with low cortisol levels. In acute uvitis in the presence of RD, the mean serum content of this hormone was significantly lower than that in infectious and idiopathic uveitis.

[Immunogenetic criteria for uveitis development in the population of the Republic of Bashkortostan].

Based on the association of certain histocompatibility Class I antigens with uveitis in patients from the Republic of Bashkortostan it has been proven that HLA B27 and B47 and haplotype A2B47 should be considered to be the markers responsible for the occurrence of uveitis in systemic and syndromic diseases. The greatest relative risk of herpetic anterior and posterior uveitis is associated with HLA B44 and B51 antigens; the risk of anterior and posterior uveitis is related to HLA B27 and HLA A28, A29 and B53, respectively. The findings permit improvement of the quality of early diagnosis of these diseases and are recommended for use in ophthalmological practice.

[Imbalance of alpha- and gamma-interferon levels in patients with herpetic keratitis].

The paper presents data on elevated serum and lacrimal fluid alpha- and gamma-interferon (INF) levels in patients with herpetic keratitis (HK) in the course of the disease depending on its clinical form and stage. A more significant increase in the levels of alpha- and gamma-INF was noted in the lacrimal fluid, which was indicative of the important role of local antiherpetic corneal and conjunctival protection. The determination of serum and lacrimal fluid IFN levels in patients with HK may be used to predict the clinical course of the disease.