Publications by authors named "V B Dohe"

Article Synopsis
  • Drug-resistant gram-negative pathogens are a major cause of neonatal sepsis, especially in low- and middle-income countries, making it crucial to understand how these infections spread.
  • A study in Western India investigated the link between maternal and environmental colonization of these pathogens and bloodstream infections (BSIs) in neonates, enrolling over 950 pregnant women and analyzing colonization patterns alongside BSI occurrences in the NICU.
  • The findings revealed no direct connection between maternal colonization and neonatal BSIs, suggesting that the infections likely spread within the NICU environment, emphasizing the need for preventative measures in such settings.
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Background: Streptococcus pneumoniae continues to cause morbidity and mortality across the globe, with developing countries bearing the brunt of the disease. It is mainly responsible for meningitis, pneumonia and septicaemia primarily in children, elderly and immunocompromised persons. Colonisation and persistence in the human nasopharynx occur during early childhood, and it appears to be prerequisite for invasive pneumococcal disease (IPD).

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Background: In India, antimicrobial consumption is high, yet systematically collected data on the epidemiology, risk factors, and outcomes of antimicrobial-resistant infections are limited.

Methods: A prospective study of adults and children hospitalized for acute febrile illness was conducted between August 2013 and December 2015. In-hospital outcomes were recorded, and logistic regression was performed to identify independent predictors of community-onset antimicrobial-resistant infections.

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Human dirofilariasis is a rare infection caused by filarial worms of genus Dirofilaria. Subconjunctival dirofilariasis has been reported from Asia, Europe, Italy and Africa. In India majority cases are from Kerala, Karnataka and very few from Maharashtra.

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