Publications by authors named "V B Dobler"

Article Synopsis
  • Over 3000 young people under 18 are admitted to mental health services in the UK annually, and this study seeks to compare intensive community care services (ICCS) against standard treatment (TAU) for those in psychiatric emergencies.
  • The research will track outcomes like educational engagement and overall well-being over a 6-month period through a multicenter randomized controlled trial involving participants from various NHS organizations.
  • This trial is significant as it aims to be the first major study assessing the clinical and cost-effectiveness of community care compared to traditional methods for addressing youth mental health crises in Great Britain.
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Background: How we adapt treatment algorithms to complex, clinically untested, difficult-to-engage patient groups without losing evidence base in everyday practice is a clinical challenge. Here we describe process and reasoning for fast, pragmatic, context-relevant and service-based adaptations of a group intervention for unaccompanied minor asylum seekers (UASC) arriving in Europe. We employed a distillation-matching model and deployment-focused process in a mixed-method, top-down (theory-driven) and bottom-up (participant-informed) approach.

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Background: Children and young people's (CYP) mental health is worsening, and an increasing number are seeking psychiatric and mental health care. Whilst many CYPs with low-to-medium levels of psychiatric distress can be treated in outpatient services, CYPs in crisis often require inpatient hospital treatment. Although necessary in many cases, inpatient care can be distressing for CYPs and their families.

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Unlabelled: Approximately half of the world's displaced population are children and a significant proportion of these are unaccompanied asylum-seeking children (UASC). UASC are the most vulnerable of all refugee populations. Up to 90% of UASC have been subjected to exploitation, including trafficking or being drafted into military groups.

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Article Synopsis
  • Childhood adversity (CA) is linked to increased risk of mental illnesses, but how it affects the hypothalamic-pituitary-adrenal axis (HPAA), a system that responds to stress, is not well understood.
  • A study analyzed cortisol levels in high-risk individuals for severe psychopathology versus healthy controls, looking at baseline cortisol, stress responses, and non-stress conditions to see how CA and current depressive symptoms relate to HPAA functioning.
  • Findings suggest that different HPAA components react distinctly to CA and depression, indicating that cortisol responses grow more complex and that future research should separate these components for better understanding.
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