[Non-neurogenic activators of myocyte contraction and their role in the realization of the accumulative-evacuating functions of the urinary bladder].

The search for and use of alternative biomarkers of the hyperactive bladder has garnered increasing attention in recent years because they may be considered pathogenetically significant and used as surrogate biomarkers. Promising agents that have met these criteria include proteins cytokines, neurotrophins, tumor necrosis factor (TNF), nerve growth factor (NGF), fibrinopeptides A and B, C-reactive protein, membrane-bound ATPase. Analysis of current scientific literature has demonstrated that specialists in many fields of medicine show interest in endogenous proteins that do not belong to neurotransmitters but affect the contractile ability of myocytes.

[Clinical-biochemical and immunological parameters in the diagnosis and treatment of chronic pyelonephritis on the background of intercurrent diseases].

Studies have shown that complicated chronic pyelonephritis in the active phase is characterized by structural and functional instability cytomembranes and decreased immunological resistance of the patient man. Supplement standard antibiotic treatment with ozone therapy antioxidant immunomodulation drug thus received immunobiochemical study.

Functional and metabolic changes in the brain in neuropathic pain syndrome against the background of chronic epidural electrostimulation of the spinal cord.

Changes in functional and metabolic activities of the brain were evaluated by EEG and positron-emission/computer tomography with 18F-fluorodeoxyglucose in patients with neuropathic pain syndrome previous to and 3 months after implantation of a system for chronic epidural spinal cord stimulation. In most cases, the use of a nerve stimulator was followed by alleviation of neuropathic pain and partial normalization of functional and metabolic activities of brain structures responsible for pain perception, emotiogenic, behavioral, and autonomic responses.

[The diagnosis and treatment of common diseases detected during medical examination of male oil-extracting industry workers].

Aim: To study the health status of male shift workers engaged in oil-extracting industry in the Tyumen Region through prophylactic medical examination, to elaborate measures for the diagnosis and treatment of the most common diseases of the viscera and urogenital system (UGS).

Subjects And Methods: In 2009, the exit team of the Unit of Preventive Examinations, Tyumen Regional Clinical Hospital, examined 1120 male shift workers of the oil-field facilities of the Tyumen Region.

Results: The health of the examined shift workers was generally better than the national and regional indices.