Publications by authors named "V Aparna"
We present the Manually Annotated GONG Filaments in H-alpha Observations (MAGFiLO v1.0) dataset. This dataset contains 10,244 annotated filaments from 1,593 observations captured by the Global Oscillation Network Group (GONG), spanning the years 2011 through 2022.
View Article and Find Full Text PDFA novel and highly selective 5--- aldol condensation of 6-ketoaldehydes is presented using a proline-based alkylphosphonium ion catalyst. Bulky and oxophilic phosphonium ion plays a vital role in facilitating kinetic aldenamine formation and activating keto groups for aldol addition. This innovative approach exclusively targets five-membered carbo- and heterocyclic aldehydes, involving unusual aldehydes as donors and ketones as acceptors.
View Article and Find Full Text PDFArticle Synopsis
- Natural drug functionalised silver nanoparticles (H-AgNPs) were synthesized using hesperetin and show promising therapeutic potential in nano-medicine, particularly for anticancer applications.
- The study investigates H-AgNPs' interactions with calf thymus DNA (ctDNA) using various analytical techniques, confirming minor structural changes and the formation of a stable H-AgNPs-ctDNA complex.
- In vitro assays demonstrated significant cytotoxic effects of H-AgNPs on lung cancer cells (A549), with an LD50 value of 118.49 µl/ml, indicating their high anticancer activity compared to normal fibroblast cells.
The influence of nanoparticles inside the human body and their interactions with biological macromolecules need to be explored/studied prior to specific applications. The objective of this study is to find the potential of camptothecin functionalised silver nanoparticles (CMT-AgNPs) in biomedical applications. This article primarily investigates the binding stratagem of CMT-AgNPs with calf thymus DNA (ctDNA) through a series of spectroscopic and calorimetric methods and then analyses the anticancer activity and cytotoxicity of CMT-AgNPs.
View Article and Find Full Text PDFObjectives: To estimate the awareness of hepatitis B virus (HBV) and coverage of hepatitis B vaccination among dental students enrolled in dental colleges located in Andhra Pradesh.
Materials And Methods: A cross-sectional study was conducted using a prestructured questionnaire to find out the awareness of HBV and coverage of hepatitis B vaccine among dental students.
Results: A total of 2780 dental students were approached to participate in the study but only 2701 (97.