[Oxytocinase activity in pregnancy complications].

Using a simpler method for cystylaminopeptidase (oxytocinase) investigation modified by means of p-nitranilide the oxytocinase activity was examined in blood serum of 51 pregnant women with complicated pregnancy in the period of week 31-34 of gestation. Lower oxytocinase values were found in women with complicated course of pregnancy compared to those in women with physiological course of pregnancy and the same gestational age. Significantly low oxytocinase activity values were established in pregnant women with preterm uterine activity.

[Oxytocinase in pregnancy complications].

Using a simpler method for cystylaminopeptidase (oxytocinase) investigation modified by means of p-nitranilide the oxytocinase activity was examined in blood serum of 51 pregnant women with complicated pregnancy in the period of week 31-34 of gestation. Lower oxytocinase values were found in women with complicated course of pregnancy compared to those in women with physiological course of pregnancy and the same gestational age. Significantly low oxytocinase activity values were established in pregnant women with preterm uterine activity.

[Cystyl aminopeptidase during normal pregnancy].

Activity of cystylaminopeptidase (CAP) was established repeatedly in the blood serum of 40 healthy women since the 14th to the 37th week of pregnancy by means of method using S-benzyl-L-cystein-p-nitranilid as substrate. Continuous increase of values was observed, more moderate up to the 28th week, later sheerer, with a certain dispersion in examination of different women in the same length of pregnancy. No statistically significant dependency was found out by evaluating different influences on the CAP activity (weight, length, and sex of the infant, time of gestation and age of mother at delivery).