Publications by authors named "V Amitabh"

Article Synopsis
  • India is facing an increasing issue with cirrhosis, highlighting the need for new non-invasive markers, such as serum prolactin, to assess liver disease severity.
  • A cross-sectional study with 117 cirrhosis patients evaluated the relationship between serum prolactin and disease complications like ascites and hepatic encephalopathy, finding significant associations.
  • Results showed that high serum prolactin levels correlated with severe liver disease, evidenced by elevated CTP scores and complications, suggesting its potential as a reliable diagnostic marker.
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Autosomal Dominant Polycystic Kidney Disease (ADPKD) accounts for 2.6% of the patients with chronic kidney disease in India. ADPKD is caused by pathogenic variants in either PKD1 or PKD2 gene.

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Light Chain Deposition Disease (LCDD) is a rare disease characterized by deposition of monoclonal non-amyloid light chains in multiple organs. We report an unusual histologic manifestation of LCDD in a 55-year-old female patient, who presented with nephrotic syndrome and an increased serum creatinine. This case of LCDD had features of cast nephropathy on biopsy which is diagnostic of myeloma kidney, when the patient was clinically asymptomatic.

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Context: Respiratory tract infections (RTI) are common causes of morbidity and mortality worldwide. Initial antibiotic therapy in upper and lower respiratory tract infections is usually empirical. The increasing evidence of antibacterial resistance in the pathogens commonly associated with pneumonia has raised concerns about the efficacy of currently available therapies and poses a challenge to clinicians.

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