Cemento-Ossifying Fibroma of Upper Lip in a Female Child.

Cemento-ossifying fibroma (COF) is a benign tumor classified under fibro-osseous lesions characterized by the proliferation of fibrous tissue associated with the presence of osteoid or cementicle-like masses. COF of bony origin is highly neoplastic in nature compared to their soft tissue counterparts which are relatively rare. The authors here present a case report of COF arising from the left upper lip in a 10-year-old female patient.

QSAR studies on N-aryl derivative activity towards Alzheimer's disease.

A Quantitative Structure Activity Relationship (QSAR) study has been an attempted on a series of 88 N-aryl derivatives which display varied inhibitory activity towards both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), targets in Alzheimer's drug discovery. QSAR models were derived for 53 and 61 compounds for each target, respectively, with the aid of genetic function approximation (GFA) technique using topological, molecular shape, electronic and structural descriptors. The predictive ability of the QSAR model was evaluated using a test set of 26 compounds for AChE (r(2)(pred) = 0.

Investigation on fagonia cretica -its effect on hormonal profile and immunomodulation in rats.

The effect of alcoholic extracts of the aerial parts of fagonia cretica on estrous cycle and implantation in female albino rats was studied, It induced random omission of heat phase in eh estrous cycle and exhibited 100% anti implantation activity without exhibiting any toxic manifestation, However it was found to have some strong androgenic antiprogestational activity, and immunostimulating property.