Publications by authors named "V A Zimmer"
Background: Most spheroid models use size measurements as a primary readout parameter; some models extend analysis to T cell infiltration or perform caspase activation assays. However, to our knowledge, T cell motility analysis is not regularly included as an endpoint in imaging studies on cancer spheroids.
Methods: Here, we intend to demonstrate that motility analysis of macrophages and T cells is a valuable functional endpoint for studies on molecular interventions in the tumor microenvironment.
Article Synopsis
- The study analyzed data from 2013 to 2021 on patients with acute pancreatitis (AP) in a Chinese city, revealing an increase in cases linked to hypertriglyceridemia and alcohol consumption while the prevalence of biliary-related AP remained stable.
- An increase in severe acute pancreatitis (SAP) cases was noted, with a rise in prevalence from 4.97% to 12.2% over the years, and male patients were found to have a higher occurrence of AP compared to females.
- Additionally, the median length of stay and hospitalization costs significantly decreased, while the overall in-hospital mortality rate remained constant throughout the study period.
Primary ad-hoc tip-in mucosectomy for colitis-related erythema-like dysplasia.
Gastrointest Endosc
December 2024
The flaming and pulled up anorectal line: Ulcerative colitis-associated squamous metaplasia of the lower rectum.
Clin Res Hepatol Gastroenterol
January 2025
This study aimed to assess the spatial distribution of cortical bone canals' network through the analysis of lacunarity (Lac), fractal dimension (FD), and canal morphological parameters in the mandible (IR group, n = 7) of human patients under radiotherapy in comparison with non-irradiated younger (yC group, n = 8) and older (oC group, n = 8) individuals. Patients who underwent mandibular surgery were selected to have bone fragments removed during surgery, and undecalcified histological slides were analyzed by phase-contrast microscopy by two operators. The following morphological parameters were assessed in the Haversian canal (Ca): area (Ca·Ar, μm), perimeter (Ca·Pm, μm), and circularity (Ca.
View Article and Find Full Text PDF