[The prospects of improving efficacy in the treatment of nephrolithiasis].

In 83.7% of patients with nephrolithiasis the morpho-functional disorders of urinary ways were disclosed. The complex of pathogenetically substantiated treatment of such patients was proposed.

[Structural changes in membranes of proliferating leukocytes L-41 as affected by low doses of ionizing radiation].

The dose-dependent effects of gamma-radiation on the leucocyte cultures L-41 has been investigated. Irradiation by the dose of 0.25 Gy stimulates the cell proliferation while that by the doses of 1.

[Molecular mechanisms of damage to fractionated liver chromatin by tetrachloromethane].

Impairing effects of tetrachloromethane on genetic apparatus were shown to consist in its high affinity and binding to transcriptionally active fraction of chromatin and subsequent destruction of DNA. As a result of the impairment the density of the chromatin fraction was increased which expressed as elevated stability to hydrolysis by endogenous nucleases. At the same time, content of single-stranded structures enriched with proteins was increased in the DNA of the transcriptionally active fraction of chromatin.