Publications by authors named "V A Yanovsky"

Unlabelled: In otorhinolaryngology, the question of improving the tactics of early postoperative management in patients who have undergone surgery on the structures of the nasal cavity remains open. The timing of rehabilitation, the possible outcome of postoperative inflammation of the mucous membrane and the patient's ability to work depend on the choice of tactics. The nasal cavity differs from other anatomical areas in its rich blood supply, and therefore the problem of adequate hemostasis in the early stages after undergoing surgical treatment is still extremely relevant.

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Article Synopsis
  • Adhesion of the middle turbinate to the nasal cavity and synechia in the middle meatus are common causes for failed surgeries in chronic sinusitis patients.
  • The study introduces a new intranasal splint, designed with 3D modeling and made of biocompatible material, to prevent these complications post-surgery.
  • Initial testing with 20 volunteers showed the splint is safe, comfortable, and effective in preventing synechiae, but further research with a larger group is needed to confirm its clinical effectiveness.
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The pharmacokinetic properties of dihydroquercetin (DHQ) were studied after single and repeated (for 3 days) administration to rats in the form of a starch suspension at a dose of 25 mg/kg. Blood samples were collected using a permanent catheter in the jugular vein in 2, 5, 10, 20, and 30 min and in 1, 2, 4, and 6 h after administration. Before the repeated administration (5 min), blood sample was collected to assess the concentration of DHQ at the zero time point.

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Taxifolin (TFL) is a small drug molecule with a broad therapeutic potential limited by its poor aqueous solubility and excessive metabolism. Despite comprehensive research, some aspects of the TFL pharmacokinetics, e.g.

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The energy and velocity distributions of ideal gas particles were first obtained by Boltzmann and Maxwell in the second half of the nineteenth century. In the case of a finite number of particles, the particle energy distribution was obtained by Boltzmann in 1868. However, it appears that this distribution is not valid for all vessels.

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