[Role of and genes polymorphisms in the pathogenesis of stroke of the Erzya population in the Republic of Mordovia].

Aim: To determine the frequency of GPIIIa and eNOS genes polymorphisms in patients with ischemic stroke in the Erzya population in the Republic of Mordovia.

Material And Methods: An open, prospective, randomized study included 4 groups: 1) Erzya with ischemic stroke (main group, n=65), 2) Russians with ischemic stroke (comparison group, n=60), 3) Erzya healthy volunteers (control-1, n=63), 4) Russian healthy volunteers (control-2, n=61). T1565C polymorphism of GPIIIa gene (rs5918) and G894T polymorphism of eNOS gene (rs1799983) were determined by real-time PCR.