Immunological and radioimmunological studies in food allergy.

Experiments in order to induce food allergy were carried out in guinea pigs. The sensitization with egg albumin, pasteurized cow milk and bovine serum albumin provoked anaphylactic shock. The passive cutaneous anaphylaxis, serum antibodies, liver cytochrome P-450 concentration and the anaphylactic shock were determined.

[Breakdown of the soluble soybean antigen in the digestive tract of adult rats].

Adult male Wistar rats received intragastrically a protein mixture containing 3H-labeled reserve protein of soy beans (PSB), the soy protein isolate 500-E of Ralston Purina Co (USA) being chosen as a protein source. Immunoreactive and TCA-precipitable 3H-PSB was determined in the stomach and small bowel content, 20 and 60 minutes after the administration. The experiment showed more complete inactivation of soy antigen as compared to chick ovalbumin (the authors' data), bovine serum albumin, chick ovomucoid and Kunitz trypsin inhibitor (the literature data).