[Effects of bilateral deep brain stimulation in the subthalamic nucleus using two methods of target structure verification].

Aim: To evaluate the efficacy of deep brain stimulation in the subthalamic nucleus (DBS STN) in patients with Parkinson's disease (PD) using different methods of targeting according to the dynamics of motor symptoms of PD.

Material And Methods: The study involved 90 patients treated with DBS STN. In 30 cases intraoperative microelectrode recording (MER) was used.

Physiology of midbrain head movement neurons in cervical dystonia.

Background: Early theories for cervical dystonia, as promoted by Hassler, emphasized the role of the midbrain interstitial nucleus of Cajal. Focus then shifted to the basal ganglia, and it was further supported with the success of deep brain stimulation. Contemporary theories suggested the role of the cerebellum, but even more recent hypotheses renewed interest in the midbrain.

Preliminary results of chronic intrathecal therapy in treatment of spastic syndromes of various etiologies.

Objective: To estimate the effectiveness of the chronic intrathecal baclofen infusion (ITB) for the treatment of botuloresistant spastic disorders.

Material And Methods: ITB have been performed in 15 cases of spastic disorders. In 8 cases spasticity was the result of cerebral palsy, 5 - spinal cord injure, 1 - cerebral injure, 1 - pyogenic spinal epiduritis.

Chronic Spinal Cord Stimulation in the Treatment of Cerebral and Spinal Spasticity.

Objectives: The aim of this investigation is to assess the effectiveness of spinal cord stimulation (SCS) in different groups of patients with spasticity of different origin.

Materials And Methods: A retrospective study of the use of the method of SCS in 71 patients. The patient population was divided into two groups: 52 cerebral palsy (CP) cases and 19 patients diagnosed with spasticity caused by spinal injury.

[Pharmacotherapy accompanied by deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease].

Aim: To analyze pharmacotherapy accompanied by deep brain stimulation of the subthalamic nucleus.

Material And Methods: The study included 54 patients, who underwent bilateral STN DBS from 2003 to 2012. The severity of motor disturbances, activities of daily living and complications of dopaminergic therapy were estimated in accordance with II, III and IV parts of the Unified Parkinson's Disease Rating Scale (UPDRS) before operation and one, three and four years after it.