Dietary nitrate supplementation very slightly mitigates the oxidative stress induced by high-intensity training performed in normobaric hypoxia.

Oxidative stress is augmented under hypoxic environments, which may be attenuated with antioxidant supplementation. We investigated the effects of dietary nitrate (NO-) supplementation combined with high-intensity training performed under hypoxic conditions on antioxidant/pro-oxidant balance. Thirty trained participants were assigned to one of three groups - HNO: hypoxia (13% FO) + NO-; HPL: hypoxia + placebo; CON: normoxia (20.

Implementation of the cascade of care for latent mycobacterium tuberculosis infection in people living with HIV/Aids.

Objective: To describe the outcome indicators of implementing a cascade of care for latent Mycobacterium tuberculosis infection in people living with the human immunodeficiency virus.

Method: Cross-sectional study, carried out with people living with HIV, from 2022 to 2024, in a reference service in Campo Grande, Mato Grosso do Sul. It occurred after the implementation of the following work process: Identification of people at risk for investigation of Latent Tuberculosis Infection (LTBI); Test for LTBI; Exclusion of active TB cases; Treatment for LTBI; Adherence to treatment; and Completion of treatment.

Comparison between Warm-Up Protocols in Post-Activation Potentiation Enhancement (PAPE) of Sprint and Vertical Jump Performance in a Female Futsal Team.

The aim of this study was to examine the influence of three warm-up protocols, with and without post-activation performance enhancement (PAPE), on sprint and vertical jump performance in female athletes. Twenty-five university futsal athletes were randomly assigned to three protocols: i) Traditional Warm-Up (TWU), involving cardiovascular, coordination exercises, and dynamic stretching; ii) Drop Jump Warm-Up (DJWU), consisting of drop jumps from heights of 30 and 40 cm; and iii) Maximum Isometric Warm-Up (MIWU), with high-intensity isometric contractions held for 10 seconds in a squat position at approximately 130-135 degrees of knee flexion. Tests included the countermovement vertical jump (CMVJ) and a 20-meter sprint (S20).

Purification, characterization, and inhibition studies of a new acetylcholinesterase obtained from the neotropical brown stink bug Euschistus heros.

We purified acetylcholinesterase from adult Euschistus heros stink bugs (AChEeh) a pest that damages economically important crops by affinity chromatography. An AChEeh inhibitor was bound to the resin, which provided selectivity for the enzyme and yielded 6.82 % of pure AChEeh.

Bone marrow-derived dendritic cells play a role in attenuating inflammation on Bothrops jararacussu venom muscle damage.

The immune system is regulated by dendritic cells (DCs), which are highly specialized cells for presenting antigens. They are thought of as natural sentinels that start the immune response triggered by naive T cells against invasive infections. DCs participate in the initial stage of muscle damage in conjunction with monocytes, macrophages, and myogenic cells.