Anticandidal Activity of In Situ Methionine γ-Lyase-Based Thiosulfinate Generation System vs. Synthetic Thiosulfinates.

and non-albicans species are a common cause of human mucosal infections, as well as bloodstream infections and deep mycoses. The emergence of resistance of spp. to antifungal drugs used in practice requires the search for new antimycotics.

[Surgical anatomy of the peri-insular association tracts. Part I.The superior longitudinal fascicle system].

Aim: To study the peri-insular association tract anatomy and define the permissible anatomical boundaries for resection of glial insular tumors with allowance for the surgical anatomy of the peri-insular association tracts.

Material And Methods: In an anatomic study of the superior longitudinal fascicle system (SLF I, SLF II, SLF III, arcuate fascicle), we used 12 anatomical specimens (6 left and 6 right hemispheres) prepared according to the Klingler's fiber dissection technique. To confirm the dissection data, we used MR tractography (HARDI-CSD-tractography) of the conduction tracts, which was performed in two healthy volunteers.

Malignant B-сell lymphoma of the anterior visual pathway.

This work was aimed at studying the optimal diagnosis methods and features of clinical signs of malignant B-cell lymphoma of the anterior visual pathways and choosing the most reasonable treatment method. Six immunocompetent patients with lymphomas in the chiasm-sellar region were examined. The outcomes of high-dose methothrexate chemotherapy and radiotherapy in these patients are analyzed.

Intraparenchymal brainstem schwannomas: report of three cases and literature review.

We report three patients with intraparenchymal brainstem schwannomas that were confirmed by surgery and pathological examination: tumors originated from the midbrain parenchyma, the dorsal aspect of the pontomedullary junction and the medulla oblongata respectively. Two of the presented patients differed in age of disease presentation which may reflect different mechanisms of tumor development according to the current views on origin of intraparenchymal schwannomas. One of the cases illustrates treatment of non-communicating hydrocephalus associated with ventricular tumors by preventive stenting of the cerebrospinal fluid pathways.

[Methods of intraoperative control in resection of intraparenchymal brain tumors].

Primary CNS tumors represent 1.4% of all malignant neoplasias and 2.4% of total oncological mortality.