The Caucasus and surrounding areas, with their rich metal resources, became a crucible of the Bronze Age and the birthplace of the earliest steppe pastoralist societies. Yet, despite this region having a large influence on the subsequent development of Europe and Asia, questions remain regarding its hunter-gatherer past and its formation of expansionist mobile steppe societies. Here we present new genome-wide data for 131 individuals from 38 archaeological sites spanning 6,000 years.
View Article and Find Full Text PDFStud Health Technol Inform
August 2024
Pharmaceutical manufacturing is a complex process, where each stage requires a high level of safety and sterility. Personal Protective Equipment (PPE) is used for this purpose. Despite all the measures of control, human factor (improper PPE wearing) causes numerous losses for human health and material property.
View Article and Find Full Text PDFWater-soluble nanocomposites based on CdSe/ZnS quantum dots (QDs) and hydrophobic tetraphenylporphyrin (TPP) molecules passivated by chitosan (CS) have been formed. Magnetic circular dichroism (MCD) spectra evidence TPP presence in both monomeric and agglomerated forms in the nanocomposites. The nanocomposites demonstrate more pronounced singlet oxygen generation compared to free TPP in CS at the same concentration due to the intracomplex Förster resonance energy transfer (FRET) with a 45% average efficiency.
View Article and Find Full Text PDFMagnetic-luminescent composites based on semiconductor quantum dots (QDs) and superparamagnetic iron oxide nanoparticles (SPIONs) can serve as a platform combining visualization and therapy. Here, we report the construction of QD-SPION nanocomposites based on synthesized SPIONs and alloyed QDs (CdxZn1-xSeyS1-y)/ZnS solubilized with L-cysteine molecules. The study of the spectral-luminescence characteristics, the kinetics of luminescence decay show the composite's stability in a solution.
View Article and Find Full Text PDFArchaeological and archaeogenetic evidence points to the Pontic-Caspian steppe zone between the Caucasus and the Black Sea as the crucible from which the earliest steppe pastoralist societies arose and spread, ultimately influencing populations from Europe to Inner Asia. However, little is known about their economic foundations and the factors that may have contributed to their extensive mobility. Here, we investigate dietary proteins within the dental calculus proteomes of 45 individuals spanning the Neolithic to Greco-Roman periods in the Pontic-Caspian Steppe and neighbouring South Caucasus, Oka-Volga-Don and East Urals regions.
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