[Development of approaches to studying the structural and functional organization of protein molecules aboard the International space station].

To solve the problems of biological safety of the cosmonaut on long-duration space mission and prediction of changes in macroorganism as a whole and constituting protein molecules under these conditions, it is important to study the influence of spaceflight factors (SFF) on microorganisms-carriers of modeled structures, protein molecules and pro- and eukaryotic genes in particular. Within the framework of scientific cooperation NAUKA-NASA, the authors proposed a model system of prokaryotic producers of pro- and eukaryotic proteins--staphylococcus alpha-toxin (SAT)--as a key protein in pathogenesis of staphylococcal infections, and human leukocytic interferon (HuIFN-alpha) as one of the homeostasis regulating proteins with well-studied structural and functional properties. Recombinant strains of E.

Baltic soil survey: total concentrations of major and selected trace elements in arable soils from 10 countries around the Baltic Sea.

Agricultural soils were collected from 10 European countries over a 1,800,000 km2 area surrounding the Baltic Sea. The sampling density was 1 site/2500 km2. Two samples were taken at each site: topsoil 0-25 cm (ploughing layer, Ap-horizon) and subsoil (bottom samples, usually B- or C-horizon) at an approximate depth of 50-75 cm, well below the ploughed layer.

[The effect of distribution of adjacent amino acids in primary structures on the possibility of mutation substitutions in globular proteins].

Frequency distributions of adjacent ARs in the primary structures of 320 globular proteins out of different superfamilies were investigated. ARs of every type were compared with the occurrence frequencies of 20 canonic residues at the distances of 1-20 residues according to their primary structure. Amino acid residues were found to be divided into groups of interchangeable residues in the course of globular protein evolution according to the distribution kinds and in terms of Euclidean distances.