Publications by authors named "V A Kurkin"
Article Synopsis
- Plant extracts, particularly from hops, show strong antimicrobial activity against Staphylococcus aureus strains, effective in both free-floating and biofilm forms, making them viable for oral care.
- The hop extract worked as well as standard antibiotics (amikacin, ciprofloxacin, and ceftriaxone) and exhibited synergy, enhancing the effectiveness of these antibiotics against various bacterial isolates.
- Chemical analysis of the extract identified key compounds (prenylated flavonoids and acylphloroglucides) that contribute to its antimicrobial effects and ability to reduce the minimum inhibitory concentration (MIC) of antibiotics, suggesting its potential as both an antiseptic and a complement to conventional treatments.
Cherula and sticklewort tinctures exhibit rapid and short-lasting diuretic effect. Tinctures of tansy and immortelle are featured by rapid onset of the effect and prolonged action, while the tincture of common bearberry has a long latency period and prolonged action. Under normal conditions of gravity, flavonoid rutin stimulates diuresis only through tubular component; under hypergravity, simultaneously via glomerular and tubular components.
View Article and Find Full Text PDFThe in vitro effect of phytosubstances containing flavonoids and phenylpropanoids on the antilysozyme activity of varioous groups of microorganisms, such as staphylococci, bacilli, enterobacteria and nonfermenting bacteria was studied. The second fraction of the pink carbonic acid extract showed high antioxidant activity and most efficiently inhibited the ability of various microorganisms to inactivate the host lysozyme. The selected phytosubstance could be useful in clinical practice as an additional antimicrobial agent in etiotropic therapy or prophylaxis of some infections.
View Article and Find Full Text PDFThe results of study on substantiating the possibilities of the use of flavolignans of Silybum marianum (L.) Gaertn. with a purpose to create a new fat product--butter fortified by an "Liguid extract Silybum marianum (L.
View Article and Find Full Text PDFFrom the herb of AERVA LANATA six alkaloids were isolated. Canthin-6-one ( 1) and beta-carboline-1-propionic acid ( 5) have been found previosly while 10-methoxy-canthin-6-one ( 2), 10-hydroxy-canthin-6-one ( 3),10- O-beta- D-glucopyranosyloxycanthin-6-one ( 4), 6-methoxy-beta-carboline-1-propionic acid ( 6) are new alkaloids. Their structures were determined by means of spectoscopic analysis and chemical transformations.
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