Efficacy of Micronized Purified Flavonoid Fraction-Based Venoactive Therapy After Endovenous Mechanochemical Obliteration: Prospective Comparative Study.

Background: Endovenous interventions and minimally invasive open procedures are effective in the management of varicose veins, but can result in post-operative pain/discomfort.

Objective: The objective of this study was to evaluate the clinical efficacy of micronized purified flavonoid fraction venoactive therapy for postoperative pain, vein-specific symptoms, and quality of life in patients with varicose veins following an endovenous mechanochemical ablation procedure.

Methods: This prospective, observational, single-center study allocated patients into two groups: Group A, micronized purified flavonoid fraction 1000 mg once daily for 30 days; Group B, no venoactive drug prescribed (control).

[The immunoregulating action of reamberine and its use in the treatment of duffuse peritonitis].

Influence of reamberin on dynamics of functional condition of mitogen-induced immunocompetent blood cells at patients with widespread purulent peritonitis is studied. It is established that investigated immunocompetent cells have regulating effect on migration of neutrophil leukocytes at widespread purulent peritonitis during all postoperative period. PHA-activated mononuclear cells don't cause inhibition of migration of neutrophil granulocytes, observed in norm.

[Free-radical oxidation in liver during experimental widespread purulent peritonitis].

One of the most powerful damaging factors during inflammation is hyperactivation of the free-radical oxidation processes. The condition of lipid peroxidation (LPO) and antioxidant activity (AOA) systems in liver has been studied in experiment on 55 male Chinchilla rabbits with widespread purulent peritonitis (WPP) model. The development of WPP leads to expressed of free-radical oxidation processes in liver that is manifested by systemic accumulation of toxic LPO products and a decrease in the activity of antioxidants.

[The use of cytoflavin in sports nutrition].

Sports nutrition for 35 athletes was supplemented by the metabolic preparation cytoflavin 1 month before a pre-competition training camp. Their physical status was estimated using a specialized Omega-C hardware-software complex. It was shown that cytoflavin promotes physical fitness of the athletes by improving energy supply, psychoemotional conditions, and competition form.

[Correction of bioenergetic processes in small intestine during experimental widespread purulent peritonitis].

The functional activity of mitochondria of the muscular coat of small intestine (MCSI) has been studied in the normal state and under experimental widespread purulent peritonitis (WPP) conditions. The experiments have been carried out on a group of 55 male rabbits of chinchilla breed. It is established that, as a result of the WPP development, the functional activity of mitochondria in MCSI considerably decreases.