Collagen Peptides from Hyaline Cartilage for the Treatment and Prevention of Joint Diseases: Isolation and Characteristics.

We studied the effects of Chymopsin and Caripazim on the proteolysis of collagen proteins from cattle tracheal hyaline cartilage. Homogenization of the cartilage under conditions of high pressure and temperature facilitated subsequent enzymatic hydrolysis: the degree of hydrolysis increased upon elevation of pressure from 40 to 80 mPa and temperature from 60 to 70°C. Proteolysis with Chymopsin yielded collagen peptides with molecular weights from 900 to 7000 Da, while Caripazim processing yielded collagen peptides with lower molecular weights from 250 to 780 Da consisting of 2-8 amino acids, which could be easily absorbed and intensely incorporated in the formation of the joint tissue structures.

Development of Low-Molecular Weight Collagen Peptide Complex with Glycosaminoglycan Components.

Enzymatic hydrolysis of biopolymers of the cartilage tissue was studied for obtaining a complex of type II collagen peptides and glycosaminoglycan oligosaccharides. Hydrothermal hydrolysis in a high pressure homogenizer followed by enzymatic hydrolysis of the cartilage tissue biopolymers with proteolytic enzyme preparation Karipazim yielded a complex of collagen peptides and glycosaminoglycan oligosaccharides with molecular weights of 240-720 Da. Low molecular weight of the components increases their bioavailability.

[Major risk factors and cardiovascular disease prevalence among petrochemical workers].

Objective. Based on the assessment of occupational and non-occupational risk factors, development of preventive measures for the reducing of cardiovascular diseases (CVD) prevalence among petrochemical workers. Material and Methods.

[Hygiene and the spectral energtic light pattern].

There are considered methodological bases of multicriteria synthesis of a spectral energetic pattern for the evaluation of the excessive share of blue and red light in the spectrum of artificial energy sources. The basis of this methodology is relied upon on the hygienic approach to the spectrum analysis of solar and led light. Relying upon on "photobiological paradox of vision" according to M.

[WORKLOAD OF PASSENGER TRAIN DRIVER AT DIFFERENT ROADS AND DRIVING REGIMES].

There was performed a chronometer study of the workload of passenger train drivers in the work in the areas of circulation differing in the complexity of the track profile and in working in various modes of conducting the train. As a result of the chronometer study of the workload of passenger train drivers in the work in the areas of circulation differing in the complexity of the track profile there was determined the structure of the workload of the operational activity of drivers and revealed the dependence of the increase in the number of control actions in the complication of the track profile. Analysis of data obtained as a result of the study of patterns of the activity in the manual mode and with the use of the automatic driving system showed a marked decrease in active control actions, but also revealed the growing problem of physical inactivity among train drivers.