[Prognostic scale for early detection of various postoperative complications after thoracic aortic surgery: post-hoc analysis of biomarkers].

Objective: To create the prognostic scale based on some biomarkers after thoracic and thoracoabdominal aortic repair.

Material And Methods: We analyzed 114 patients with aortic aneurysm/dissection. The following biomarkers were studied: proadrenomedullin, NT-proBNP, procalcitonin, interleukins 6, 8, 10, tumor necrosis factor, presepsin, highly sensitive troponin I.

[The efficacy and safety of tranexamic acid and epsilon-aminocapronic acid in cardiac surgery under extracorporeal circulation].

Sixty patients who had undergone cardiosurgical operations under extracorporeal circulation (EC) were enrolled in the study. All the patients were divided into 2 groups: (1) 40 patients were injected tranexamic acid (TA) (its loading dose was 15 mg/kg; maintenance infusion 1 mg/kg/h throughout the operation; 500 mg in the primary packing volume for an EC apparatus (EA); (2) 20 patients received epsilon-aminocapronic acid (ACA) (its loading dose was 5 g; 5 g in the primary packing volume for an EA and 10 g for infusion after EC). The effects of TA and ACA on the fibrinolytic system were evaluated from the time of XIIa-kallikrein-dependent fibrinolysis (sec) and the concentration of D-dimer (mg/ml).

[Conditions of artificial blood circulation and erythrocytic aggregation in cardiosurgical patients].

Normothermic artificial circulation, irrespective of its duration, enhances erythrocyte aggregation in response to noradrenaline stimulation. Short-term hypothermic perfusion reduces adrenergic aggregation of erythrocytes while in long-term hypothermic artificial circulation changes in erythrocyte adrenergic aggregation are not significant. In the course of cardiosurgical operation in conditions of artificial circulation adrenergic erythrocyte aggregation undergoes changes: a maximal rise before perfusion, linear lowering and rise to the preoperative level.

[Comparative assessment of criteria for postoperative renal dysfunction in cardiosurgical patients].

The paper presents data on comparison of the detection rate of renal dysfunction after cardiac surgery, by using the criteria developed by Cockroft-Gault, C. M. Mangano, L.