[Inflammatory reaction and sepsis in pancreatic necrosis].

Analysis of clinical data, results of treatment, and the development of systemic inflammatory reaction (SIR) in 100 patients with sterile or infective pancreonecrosis and pancreatogenic necrosis demonstrated a phase-wise pattern in the development of inflammatory and septic process in pancreonecrosis. The development of inflammation and sepsis in such patients is determined by the extent of involvement, infection of necrotic zone, and disease duration. SIR, shock, and polyorgan failure are the cardinal components in the pathogenesis of various phases of pancreonecrosis.

[Prevention of hemodynamic disorders during anesthesia in middle-aged and elderly patients with essential hypertension. Components of anesthesia. II].

Hemodynamic parameters were evaluated during various stages of anesthesia in two groups of patients aged 60-85 years with mild essential hypertension. In group 1, routine preoperative treatment with hypotensive drugs was carried out and in group 2 differentiated preoperative treatment with calcium antagonists was carried out with consideration for a hemodynamic type. Group I patients were operated on under traditional neuroleptic analgesia (NLA), group 2 under NLA with 40% lower drug doses than in group 1 and with addition of calcium antagonists.

[Prevention of postoperative venous thromboembolic complications].

Venous thromboembolic complications (VTEC) occurring during the postoperative period notably increase the mortality. Prevention of this complications requires detection of risk factors in order to evaluate the risk for every patient. Based on the risk factors described in this paper, all patients can be divided into categories at a high, moderate, and low risk of complications.

[Abdominal sepsis: the integral assessment of the severity of patient condition and of multiple organ dysfunction].

Results of examinations of 247 patients with diffuse peritonitis and symptoms of abdominal sepsis are analyzed. Systemic inflammatory reaction in peritonitis patients can manifest by sepsis, severe sepsis, and infectious toxic (septic) shock. The severity of systemic inflammatory reaction syndromes can be evaluated by objective scores for evaluation of clinical states (APACHE II, SAPS) and the degree of multiple organ dysfunction/failure (MODS, SOFA).