Publications by authors named "V A Fleetwood"
Background: Recent studies suggest that approximately 10% of patients with chronic kidney disease (CKD) have disease-causing genetic variants, an observation relevant to evaluation of kidney transplant candidates.
Methods: We retrospectively investigated the diagnostic yield of genetic testing in kidney transplant candidates evaluated at our program (January 1, 2021-December 8, 2022). Inclusion criteria were as follows: first-degree relative(s) with CKD/end-stage kidney disease (ESKD), early-onset CKD, focal segmental glomerulosclerosis, cystic kidney disease, alternative complement pathway-associated diseases, or ESKD of unknown cause.
Article Synopsis
- Gangrenous cholecystitis is a severe complication stemming from acute cholecystitis, often linked to Bacteroides infections, but can be caused by rare organisms in immunocompromised patients, like the case of a 48-year-old male with pancreatic cancer and actinomyces odontolyticus infection.
- The patient presented with severe abdominal pain and altered mental status, underwent a sub-total cholecystectomy, and was treated with multiple antibiotics, although he eventually transitioned to hospice care due to the progression of his condition.
- This case highlights the importance of considering cholecystitis in the differential diagnosis of abdominal pain in immunocompromised patients with pancreatic cancer, especially following procedures
Concerns related to poor oxygenation in patients with severe hepatopulmonary syndrome (HPS) may be prohibitive when considering their candidacy for liver transplantation. Extracorporeal membrane oxygenation (ECMO) has been utilized in only a few case reports as a bridge to liver transplant in patients with severe respiratory failure. We report a case of a 66-year-old man with cirrhosis and very severe (arterial oxygen pressure (PaO2) < 50 mmHg) hepatopulmonary syndrome who underwent an orthotopic liver transplant with the planned use of venovenous-ECMO.
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