Background: Both lung lobe segmentation and lung fissure segmentation are useful in the clinical diagnosis and evaluation of lung disease. It is often of clinical interest to quantify each lobe separately because many diseases are associated with specific lobes. Fissure segmentation is important for a significant proportion of lung lobe segmentation methods, as well as for assessing fissure completeness, since there is an increasing requirement for the quantification of fissure integrity.
View Article and Find Full Text PDFLymphovascular invasion (LVI) in lung cancer is a significant prognostic factor that influences treatment and outcomes, yet its reliable detection is challenging due to interobserver variability. This study aims to develop a deep learning model for LVI detection using whole slide images (WSIs) and evaluate its effectiveness within a pathologist's information system. Experienced pathologists annotated blood vessels and invading tumor cells in 162 WSIs of non-mucinous lung adenocarcinoma sourced from two external and one internal datasets.
View Article and Find Full Text PDFThe analysis of the microvasculature and the assessment of angiogenesis have significant prognostic value in various diseases, including cancer. The search for invasion into the blood and lymphatic vessels and the assessment of angiogenesis are important aspects of oncological diagnosis. These features determine the prognosis and aggressiveness of the tumor.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
March 2019
The article presents the history of development of sanitary business and state sanitary epidemiological service of the Primorskiy Krai related to general history of Russia in XIX-XX centuries. The study established input of physicians of Vladivostok into implementation of sanitary activities during first decades from city foundation: opening of the Pasteur station, struggle with epidemics of very dangerous infectious diseases, functioning of sanitary executive commission. The activities concerning support of sanitary epidemiological well-being of population during the Civil War in the Far East, years of socialism development and in post-Soviet period are considered.
View Article and Find Full Text PDFWith the use of the methodology of the system approach there were obtained results of the evaluation of the occurrence of ecology-dependent diseases in children and adolescents in bioclimatic zones of the Primorsky Krai. Analysis of the prevalence of the main classes of ecologically dependent diseases according to the appealability (diseases of the respiratory system, diseases of digestive organs, diseases of blood and blood-forming organs, diseases of the circulatory system, diseases of the skin and subcutaneous tissue, diseases of the genitourinary system, neoplasms, congenital anomalies, infectious diseases) was performed with the use of official statistical report forms No. 12 (ICD-10) over the period of2000-2014.
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