J Surg Case Rep
November 2024
Sciatic nerve pain, affecting 12%-27% of the general population, often arises from a myriad of etiologies due to the complex anatomy of the sciatic region. The intricate relationship between the sciatic nerve and surrounding structures in the pelvis poses significant challenges in both diagnosis and surgical management. We report two cases of adult female patients presenting with chronic sciatic pain, refractory to conservative treatment.
View Article and Find Full Text PDFBackground: The present study investigates whether vitamin D receptor (VDR) gene polymorphisms play a role in intervertebral disc degeneration (IDD), a common cause of low back pain (LBP) and reduced quality of life. Specifically, we examined the FokI VDR polymorphism and its potential association with lumbar disc herniation (LDH) in patients from Bulgaria. Previous studies have suggested a link between mutations in the VDR gene and IDD.
View Article and Find Full Text PDFBackground: Histones are proteins closely associated with the DNA molecules and serve as a structural scaffold for the organization of chromatin. They play an important role in the regulation of gene expression by changing the level of DNA compaction. The special subtype of the linker histone family-H1 zero (H1.
View Article and Find Full Text PDFKhirurgiia (Sofiia)
October 2010
Unlabelled: Spontaneous putaminal intracerebral haematomas (ICH) related to arterial hypertony are a relatively often type of pathology in the CNS. Classically such haematomas are operated through a transsylvian or temporal approach. With the development of minimally invasive neurosurgery and neuroendoscopy literature data appears describing an alternative path of evacuation through the frontal lobe without a determination of a separate approach.
View Article and Find Full Text PDFKhirurgiia (Sofiia)
October 2010
Epidermoid cysts represent 0.2-1% of all intracranial tumours. Extremely rare they are found in the pineal region.
View Article and Find Full Text PDFThe cranio-atlanto-axial junction (C0-C2) is anatomically and biomechanically the most complex spinal region. It is frequently engaged by different pathologies of tumoral, traumatical or inflammatory origin, leading to spinal instability. The advanced knowledge about the anatomical details, the physiology, the mechanism of injury, the nature of the processes and their classification are crucial for the adequate therapeutic approach when dealing with pathologies in this region.
View Article and Find Full Text PDFKhirurgiia (Sofiia)
December 2008
Introduction: High-grade gliomas are the most common primary brain tumors. Dismal prognosis for the patients with a marked deterioration of the quality of life and a mean length of survival of 9-18 months are typical characteristics for this pathology. The aim of this study is to assess the most appropriate questionnaire for measuring the quality of life (QOL) in this group of patients.
View Article and Find Full Text PDFKhirurgiia (Sofiia)
December 2008
Introduction: Aneurysms of the internal carotid artery (ICA)-anterior choroid artery (ACHA) are about 2-5% of all intracerebral aneurysms. The neck of the aneurysm typically engages both arteries. Aneurysms located on the ACHA itself without engaging the ICA present a rare pathology.
View Article and Find Full Text PDFIntroduction: We report a case of a 52-years old women with Paget's disease. A secondary symptomatic basilar impression was observed, causing quadriparesis, bulbar palsy and ataxia
Clinical Presentation: We report a case of a 52-year old woman with history of/periodic headache. In the last 6 months the complaints became more intensive and continuous.
Khirurgiia (Sofiia)
September 2008
Introduction: We are presenting our preliminary experience with the cervical intervertebral carbon cages (CICC) as a treatment option for interbody fusion in cases with cervical disk herniation.
Material And Methods: For the period 08.2003-08.
Khirurgiia (Sofiia)
October 2008
Introduction: The craniocervical junction (C0-C2) is anatomically and biomechanically the most complex spinal region. It is frequently engaged by different pathologies of tumoral, traumatic or inflammatory origin, leading to spinal instability. We are presenting our experience with the posterior screw fixation for the treatment of the craniocervical junction instabilities.
View Article and Find Full Text PDFOver the period January 1988 to January 1998, in the clinic of emergency neurology and neurosurgery of the University Hospital "Queen Giovanna"--Sofia a total of 348 patients with brain tumors are hospitalized. Of them 329 cases are subjected to operation, and in 19 no surgery is undertaken. Forty-four patients with metastatic brain tumors are operated, and in 14 no operation is done.
View Article and Find Full Text PDFKhirurgiia (Sofiia)
July 2000
Over the period 1994-1998, five patients presenting coagulation status impairment in the course of sintrom treatment are hospitalized in the Clinic of Emergency Neurology and Neurosurgery. Three of them are with craniocerebral trauma (2 severe forms--score 5 by the Glasgow Coma Rating scale, and one mild form--score 15), one has spontaneous intracerebral hematoma, and one--acute hydrocephalus against the background of ruptured aneurysm of the basilar artery (score 4). Three patients are given sintrom treatment because of rheumatic heart disease (2 with mitral valve prosthetic replacement and one in the post-commissurotomy period), and two--because of absolute arrhythmia, complicated by systemic emboli in the extremities and/or pulmonary artery.
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