Publications by authors named "Uzma Zaheer"

Article Synopsis
  • As life expectancy increases globally, there is a rising concern about the aging population and the associated age-related diseases (ARDs) that put pressure on healthcare systems and economies.
  • The emerging field of geroscience offers innovative strategies to understand and potentially intervene in the aging process, aiming to improve healthspan—the period of life spent in good health.
  • This review explores promising methods to modulate aging, discusses the shared mechanisms behind aging and ARDs, and identifies rational strategies for promoting healthier aging in society.
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MicroRNA (miRNAs), a class of small, endogenous non-coding RNA molecules of about 21-24 nucleotides in length, have unraveled a new modulatory network of RNAs that form an additional level of posttranscriptional gene regulation by targeting messenger RNAs (mRNAs). These miRNAs possess the ability to regulate gene expression by modulating the stability of mRNAs, controlling their translation rates, and consequently regulating protein synthesis. Substantial experimental evidence established the involvement of miRNAs in most biological processes like growth, differentiation, development, and metabolism in mammals including humans.

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