Publications by authors named "Uzel V"
Article Synopsis
- During the COVID-19 pandemic lockdown, the study assessed respiratory viral infections in children with cancer, highlighting their clinical impact.
- Of the 265 episodes evaluated, human rhinovirus/enterovirus was the most common pathogen identified, with significant complications noted, including a higher rate of lower respiratory tract infections.
- The findings emphasize the necessity for quicker detection and treatment of respiratory viruses to prevent severe outcomes in this vulnerable population.
Importance: Cancer was a common noncommunicable disease in Syria before the present conflict and is now a major disease burden among 3.6 million Syrian refugees in Turkey. Data to inform health care practice are needed.
View Article and Find Full Text PDFBackground: Thalassemia major (TM) is an inherited anaemia caused by faulty haemoglobin synthesis. Reducing serum iron levels using iron chelating agents is an important step in the treatment of TM, and the effects on the eye of both the disease and these agents can be determined by regular eye examination.
Objectives: We evaluated macular and optic nerve vascular densities in children with TM and compared the results with healthy controls using optical coherence tomography angiography (OCTA).
Objective: Although many pediatric studies on children infected with coronavirus disease 2019 (COVID-19) have been published, the diagnosis, clinical symptoms, laboratory findings, and treatment of COVID-19 in children are still unclear.
Materials And Methods: This study was conducted with an aim to examine the hematological findings of symptomatic pediatric patients diagnosed with COVID-19 in May 2020 at the Pandemic Hospital in Dicle University. Patient records were evaluated retrospectively.
Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder with recurrent fever, abdominal pain, serositis, articular manifestations, erysipelas-like erythema, and renal complications as its main features. Caused by the mutations in the MEditerranean FeVer (MEFV) gene, it mainly affects people of Mediterranean descent with a higher incidence in the Turkish, Jewish, Arabic, and Armenian populations. As our understanding of FMF improves, it becomes clearer that we are facing with a more complex picture of FMF with respect to its pathogenesis, penetrance, variant type (gain-of-function vs.
View Article and Find Full Text PDFCovid-19 in a patient with Familial Hemophagocytic Lymphohistiocytosis in children.
Turk J Pediatr
January 2022
Background: Based on the information obtained so far, COVID- 19 is relatively mild in children. We will present a 6-month-old male patient infected with COVID -19 in April 2020, while receiving HLH 2004 chemotherapy protocol with the diagnosis of familial (Genetic / Primary) Hemophagocytic Lymphohistiocytosis (HLH).
Case: Herein we present a case accompanied by a defective perforin gene defect in the primary HLH pathogenesis, Covid-19 infection with the presence of fever and hyperferritinemia, which was evaluated in favor of reactivation and the patient was given both the HLH-2004 chemotherapy protocol treatment and COVID -19 therapy as recommended by the guidelines.
Introduction Excess iron accumulation occurs mainly in organs such as reticuloendothelial cells, the pituitary gland, and the pancreas in beta-thalassemia because of blood transfusions. In the present study, it was aimed to investigate the relationship between T2* values on magnetic resonance imaging (MRI) and clinically diagnosed pituitary endocrinological disorders in children with thalassemia major. Methods This study enrolled patients diagnosed with beta-thalassemia at pediatric hematology outpatient clinics.
View Article and Find Full Text PDFArticle Synopsis
- - The study analyzed the clinical features of Covid-19 in Turkish children, finding that most cases were mild or asymptomatic, with limited symptoms like dry cough and fever.
- - Out of 105 children evaluated, the primary mode of transmission was through contact with infected family members, indicating a familial spread of the virus.
- - The findings emphasize the importance of understanding local Covid-19 trends and risk factors to enhance prevention and control measures in the pediatric population.