Publications by authors named "Uyi G Omogiade"
Problem: Preterm birth (PTB) is a significant cause of maternal and neonatal morbidity and mortality worldwide. However, the effectiveness of progesterone (P4) which is clinically used for PTB management remains controversial and necessitates research into new therapeutic options METHOD OF STUDY: In the current study, we investigated the effectiveness of two chlorophyll derivatives, pheophorbide a (PBa) and pheophytin a (PTa), in counteracting PTB. Timed-pregnant mice (gestation day 17 ± 0.
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- - We outline a method to isolate viable single ovary cells from just one mouse instead of needing multiple mice.
- - The workflow includes essential steps such as staging the estrous cycle, harvesting and dissociating the ovary, staining the cells, and analyzing the data.
- - This protocol enhances the collection of immune cells, particularly various T cell subsets, and allows for applications in flow sorting and functional assays.
Polycystic ovary syndrome (PCOS) affects up to 10% of women within reproductive ages and has been a cause of infertility and poor quality of life. Alteration in the oxidant-antioxidant profile occurs in PCOS. This study, therefore, investigates the contribution of ascorbic acid (AA) and alpha-tocopherol(ATE) on different PCOS parameters.
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