A new approach for professional dental bleaching using a polymeric catalyst primer.

Objective: Evaluate the influence of a polymeric catalyst primer (PCP) on esthetic efficacy (EE), degradation kinetics of hydrogen peroxide (H O ), and trans-amelodentinal cytotoxicity (TC) of bleaching gels.

Materials And Methods: The following groups were established: G1: No treatment (NC, negative control); G2: PCP; G3: 10% H O ; G4: PCP + 10% H O ; G5: 20% H O ; G6: PCP + 20% H O ; G7: 35% H O (positive control); G8: PCP + 35% H O . To determine EE, enamel/dentin discs (E/DDs) were stained and subjected or not to bleaching protocols for 45 min.

Manganese oxide increases bleaching efficacy and reduces the cytotoxicity of a 10% hydrogen peroxide bleaching gel.

Objective: The study aims to assess the effects of a 10% HO bleaching gel with different MnO concentrations on the bleaching efficacy (BE), degradation kinetics (DK) of HO, and trans-amelodentinal cytotoxicity (TC).

Materials And Methods: Standardized bovine enamel/dentin disks (n = 96) were placed in artificial pulp chambers, and the bleaching gels were applied for 45 min. Thus, the following groups were established: (G1) no treatment (negative control/NC); (G2) 35% HO (positive control/PC); (G3) 10% HO; (G4) 10% HO + 2 mg/mL MnO; (G5) 10% HO + 6 mg/mL MnO; and (G6) 10% HO + 10 mg/mL MnO.

Strategy for reducing cytotoxicity and obtaining esthetic efficacy with 15 min of in-office dental bleaching.

Objectives: Evaluate in vitro the esthetic efficacy and cytotoxicity of a bleaching gel containing 35% hydrogen peroxide (BG-35%HO), applied for different time intervals, on enamel coated or not with polymeric biomaterials.

Materials And Methods: Nanofiber scaffolds (NSc) and a primer catalyst (PrCa) were used to coat the bovine enamel/dentin discs before the application of BG-35%HO, according to the following groups: G1-negative control (NC, without treatment); G2, G3, and G4-BG-35%HO applied for 3 × 15, 2 × 15, and 15 min; G5, G6, and G7-BG-35%HO applied on enamel coated with NSc and PrCa for 3 × 15; 2 × 15, and 15 min, respectively. The culture medium with components of gel diffused through the discs was applied on MDPC-23 cells, which were evaluated regarding to viability (VB), integrity of the membrane (IM), and oxidative stress (OxS).

Polymeric biomaterials maintained the esthetic efficacy and reduced the cytotoxicity of in-office dental bleaching.

Evaluate the kinetics of hydrogen peroxide (H O ) degradation, esthetic efficacy and cytotoxicity of a bleaching gel with 35%H O applied on enamel previously covered or not with polymeric nanofibrillar scaffold (SNan), polymeric primer catalyst (PPol), and both. Standardized enamel/dentin discs (n = 128) obtained from bovine teeth were adapted to pulp chambers. After covering enamel with the polymeric products, the bleaching gel was applied for 45 min, establishing the following groups: G1: no treatment (negative control); G2: 35%H O (positive control); G3: SNan; G4: PPol; G5: SNan + PPol; G6: SNan + 35%H O ; G7: PPol + 35%H O ; G8: SNan + PPol + 35%H O .

Increased whitening efficacy and reduced cytotoxicity are achieved by the chemical activation of a highly concentrated hydrogen peroxide bleaching gel.

Objective: This study was designed for the chemical activation of a 35% hydrogen peroxide (H2O2) bleaching gel to increase its whitening effectiveness and reduce its toxicity.

Methodology: First, the bleaching gel - associated or not with ferrous sulfate (FS), manganese chloride (MC), peroxidase (PR), or catalase (CT) - was applied (3x 15 min) to enamel/dentin discs adapted to artificial pulp chambers. Then, odontoblast-like MDPC-23 cells were exposed for 1 h to the extracts (culture medium + components released from the product), for the assessment of viability (MTT assay) and oxidative stress (H2DCFDA).