Genome-wide analysis of G-quadruplexes in herpesvirus genomes.

Background: G-quadruplexes are increasingly recognized as regulatory elements in human, animal, bacterial and plant genomes. The presence and function of G-quadruplexes are not well studied among herpesviruses; in particular, there are no systematic genome-wide analysis of these important secondary structures in herpesvirus genomes.

Results: We performed genome-wide analysis of putative quadruplex sequences (PQS) in human herpesviruses.