Publications by authors named "Uthman A Yusuf"
Aluminium is known to accelerate oxidative stress, amyloid beta (A) deposition, and plaque formation in the brain of rats. . The present study is aimed at studying the neuroprotective effects of eugenol following aluminium-induced neurotoxicity on caspase-3, apoptotic proteins (Bcl-2 and Bax), and oxidative stress markers in Wistar rats such as superoxide dismutase (SOD), glutathione peroxidase (GPx), nitric oxide (NO), and assay oxidative stress to mitochondrial DNA (mtDNA) by measuring the levels of 8-hydroxy-2-deoxyguanosine (8-OHdG).
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- Lead exposure negatively impacts the male reproductive system, causing decreased testicular weight, lower sperm count and motility, and increased oxidative stress markers.
- The study used rats divided into three groups to test the effects of lead with one group receiving tomato paste to combat these effects over eight weeks.
- Results showed that tomato paste significantly mitigated the harmful effects of lead, particularly concerning sperm health and oxidative stress levels, though it did not affect testosterone levels.