[Effect of 3-(4-chlorphenyl-) 1-phenyl-1H-pyrazole-4-acetic acid (lonazolac-Ca), diclofenac-Na and indomethacin on the gastrointestinal blood loss].

According to a Latin Square-2 block study design gastrointestinal blood loss after medication with lonacolac-Ca (200 mg t.i.d.

[The influence of acemetacin and indometacin on gastrointestinal blood loss in normal volunteers and rheumatic patients (author's transl)].

In a clinical trial on 12 healthy volunteers total gastrointestinal blood loss was measured with 51Cr-labelled erythrocytes. This double-blind cross-over study showed a highly significant difference (p < 0.001) between indometacin and [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy[acetic acid (acemetacin, TV 1322, Rantudil¿) after oral application of 200 mg acemetacin, 200 mg indometacin per day and placebo for a week.

[Effect of furosemide on the hemodynamics of the kidney medulla during salt depletion].

Unlabelled: In sodium depleted rats cortical and medullary blood flow was studied before and after 4-chloro-N-(2-furylmethyl)-5-sulfamoyl-anthranilic acid (furosemide). 86Rb was used as an indicator of renal hemodynamics. Its activity was assessed in systemic blood and in tissue slices of the kidney.

[14CO2 exhalation tests. Diagnostic improvement in gastroenterologic diseases].

For evaluation of 14CO2-breath-tests the three most employed tests, namely glycero-14C-tripalmitate-test, 14C-lactose-tolerance-test, and 14C-glycin-cholate-test, were performed in healthy volunteers (n = 69), patients with chronic pancreatitis (n = 18), manifest malassimilation (n = 8), lactase deficiency (n = 15), and patients, in whom a disturbed enterohepatic bile salt circulation was suspected (n = 19). Usefulness of malabsorption tests was limited by many false normal results. Cholylglycin-breath-test on the other hand was sensitive, but clinical significance remained questionable.

[Differentiation of the effect of diuretic urine extracts on the renal medullary blood flow (author's transl)].

In sodium depleted rats urine extracts of hydrated healthy human volunteer cause an increase in water excretion of 52% (p less than 0.005) and in sodium excretion of 45% (p less than 0.005).

[The effect of Voltaren on the gastrointestinal excretion of blood (author's transl)].

24 subjects were treated with Voltaren 150 mg per day for 21 days, or with Naproxen 750 mg per day and ASA 3.0 g per day. In all patients the physiological excretion of blood from the intestine markedly increased, to a very great extent with Naproxen and ASA.

[Hypotonic examination of esophagus in pediatric radiology (author's transl)].

Report on 22 children whose esophagus was radiologically examined under maximum hypotonia, using i.v. Buscopan in a dose of 1 mg/kg body weight (highest 50 mg).

[New procedure in the diagnosis of maldigestion. Studies with 3-H palmitic acid and 14-C tripalmitate in normal subjects and patients with chronic pancreatitis].

3H-palmitic acid and 14C-tripalmitate dissolved in 1.0 g indian corn oil/kg body weight were administered to 29 patients with chronic pancreatitis and 25 control subjects. For the following 8 h 3H and 14C radioactivity in serum lipids and 14CO2 in expired air were measured at 2-hour intervals.