Sick leave duration as a potential marker of functionality and disease severity in depression.

To discuss the impact of depression on work and how depression-related sick leave duration could be a potential indicator and outcome for measuring functionality in depression. Our review was based on a literature search and expert opinion that emerged during a virtual meeting of European psychiatrists that was convened to discuss this topic. Current evidence demonstrates that depression-related sick leave duration is influenced by multiple disease-, patient- and work-related factors, together with societal attitudes towards depression and socioeconomic conditions.

[Dual diagnosis: depression and alcohol use disorder].

A combination of depression and alcohol use disorder (AUD) is a typical and most common example of a dual diagnosis at the intersection of general psychiatry and addiction psychiatry. A comorbidity of depression and AUD is more common than it can be brought about by mere coincidence, which might be explained to some extent by the synergetic effect of both diseases, with each of them complicating the course and worsening the prognosis of the other. Treatment protocols for patients with depression and comorbid AUD include antidepressants, specific medications for alcohol dependence, and psychotherapy.

[Agoraphobia with panic disorder combined with depression].

Objective: The aim of the study was to investigate the course of agoraphobia with panic disorder combined with the major depressive disorder to establish positive and negative prevalence predictors.

Material And Methods: The sample consisted of 49 women. The average age was 41.

[The differences in the estimation of depression severity by psychiatrists and patients during the combined treatment with agomelatine (a multicenter study "EMOTSIA")].

Aim: To compare the prognosis of depression severity estimated by the physician and by the patient based on the treatment outcome.

Material And Methods: One hundred and seven patients with depression were examined. Mental status was assessed with HАМ-D, SHAPS, CGI-S, CGI-I, PGI-S, PGI-I and VAS.

[Preparation and use of chemical disinfectants in biological protection and prevention of contagious diseases : ecological aspects].

Ecological requirements to reduce negative effects of chemical disinfectants were one on major determinants the line of works to develop and introduce novel compounds that are environmentally safe hydrogen peroxide derivatives. The paper analyzes the possible routes of entering different fluorine compounds into the environment when disinfecting measures are made at therapeutical-and-preventive institutions, when emergencies occur at microbiological synthesis plants. The maximum concentration of a chemical that has no effect on biochemical processes when it is continuously used at sewage works is chosen as a safe (permissible) level.