Publications by authors named "Usman Nurudeen Ikumapayi"
Exploring Natural Immune Responses to Exposure Using Multiplex Bead Assays on Dried Blood Spots in High-Burden Countries: Protocol From a Multisite Diarrhea Surveillance Study.
Open Forum Infect Dis
March 2024
Article Synopsis
- Molecular diagnostics have revealed a higher prevalence of shigellosis from human fecal samples than traditional culture methods, highlighting the need for improved identification of its causes.* -
- The study involves testing dried blood spots for specific antibodies to determine immune responses in individuals with shigellosis and comparing these responses among various case types to identify patterns.* -
- The findings aim to enhance our understanding of shigellosis, establish baseline immunity, and ultimately aid in the development of effective vaccines against diarrhea.*
Invasive non-typhoidal (iNTS) disease continues to be a significant public health problem in sub-Saharan Africa. Common clinical misdiagnosis, antimicrobial resistance, high case fatality and lack of a vaccine make iNTS a priority for global health research. Using whole genome sequence analysis of 164 invasive isolates obtained through population-based surveillance between 2008 and 2016, we conducted genomic analysis of the serovars causing invasive diseases in rural Gambia.
View Article and Find Full Text PDFIntroduction: Healthcare-associated infections (HAIs) are better documented in developed than in developing countries. There are emerging reports regarding the high frequency of HAIs in developing countries. We aimed to report an outbreak of an HAI caused by Serratia liquefaciens at a rural health center in The Gambia.
View Article and Find Full Text PDFObjective: To evaluate pneumococcal colonisation before and after the introduction of pneumococcal conjugate vaccine (PCV) in eastern Gambia.
Methods: Population-based cross-sectional survey of pneumococcal carriage between May and August 2009 before the introduction of PCV into the Expanded Program on Immunization. Nasopharyngeal swabs were collected from all household members, but in selected households, only children aged 6-10 years were swabbed.