[The effect of vitamin D deficiency on the content of some soluble signaling molecules in the oral fluid in individuals with dental caries].

Objective: The aim of the sthudy is to sthudy the level of soluble Immune Checkpoint Molecules (B7.2, CTLA-4, Tim-3, Lag-3, PD-1) in the oral fluid during dental caries with the background of a lack and/or deficiency of 25-hydroxy-vitamin D in body.

Materials And Methods: During the research 3 groups of people were formed, each one of them included 17 people aged from 20 to 24 years.

COVID-19 Vaccinating Russian Medical Students-Challenges and Solutions: A Cross-Sectional Study.

: The role of preventive measures increases significantly in the absence of effective specific COVID-19 treatment. Mass population immunization and the achievement of collective immunity are of particular importance. The future development of public attitudes towards SARS-CoV-2 immunization depends significantly on medical students, as future physicians.

Sucrose Is Not the Whole Story: Risk Factors and Oral Health at the Contact (Yakutia, Siberia-16th/19th).

(1) Background: contact between indigenous and European populations has often resulted in changes in oral health attributed to the introduction of sucrose. Most studies are per tooth over considerable periods and with few ethnological references. (2) Aim: dental epidemiology of 96 autochthonous frozen bodies from Yakutia between the early 17th century and the late 19th century; comparisons with historical texts and ethnographic data.

[Modern concept of pain syndrome and dental anxiety pathophysiology and prevention].

The work presents a wide range of etiological factors and pathogenesis of formation and development of the pain symptom. The conceptual model of pain which consists of the uniform process including four main complementary levels is presented: nociception, algesis, suffering and painful behavior.

[Clinical characteristic of factors and tools influencing the effectiveness and safety of local anesthesia in dentistry].

Dental health is one of the most important signs of life quality and depends on the level of health care organization. Recently the clinical odontology is intensively developing, including local anesthesia where constant searching of effective remedies and methods of suppression and treatment of pain is carried out. At the same time carrying out adequate local anesthesia has important practical value that is to some extent bound to massive visits of the patients to the clinics.

MICROBIOCENOSIS IN INFLAMMATORY PROCESSES OF MARGINAL GUM AMONG CHILDREN.

Introduction: The development of gingivitis among children remains actual problem in modern dentistry due to high prevalence, disorders of dental-alveolar functions and development of parodontium diseases at the older age. The microorganisms occupying dental chamfer play the leading role in parodontium tissues damage.

Aim: Research of microbial spectrum of dental chamfer and assessment of etiology significances of the revealed microorganisms in gingivitis among children of school age.

[Use of adaptogens for antioxidant system correction in complex treatment of mandibular fractures].

Antioxidatic protection has been studied in 84 patients with mandibular fractures between the ages of 21 and 40; the patients were divided into two groups. Activation of lipid peroxidation in both groups was revealed. The increase of antioxidant's activity system in 37.

[Structure and dynamics of congenital maxillofacial malformation in Yakutiya region].

The aim of the study was to assess structure and dynamics of congenital facial clefts prevalence in Republic Sokha (Yakutiya) in the last 13 years. Both retrospective and prospective study included 423 children with congenital facial malformations. Dynamic analysis showed cyclical changes in the incidence of cleft lip and palate (CLP) and relatively high regional prevalence of CLIP with tendency to increase.