Chiral Nanostructured Glycerohydrogel Sol-Gel Plates of Chitosan L- and D-Aspartate: Supramolecular Ordering and Optical Properties.

A comprehensive study was performed on the supramolecular ordering and optical properties of thin nanostructured glycerohydrogel sol-gel plates based on chitosan L- and D-aspartate and their individual components in the X-ray, UV, visible, and IR ranges. Our comparative analysis of chiroptical characteristics, optical collimated transmittance, the average cosine of the scattering angle, microrelief and surface asymmetry, and the level of structuring shows a significant influence of the wavelength range of electromagnetic radiation and the enantiomeric form of aspartic acid on the functional characteristics of the sol-gel materials. At the macrolevel of the supramolecular organization, a complex topography of the surface layer and a dense amorphous-crystalline ordering of polymeric substances were revealed, while at the nanolevel, there were two forms of voluminous scattering domains: nanospheres with diameters of 60-120 nm (L-) and 45-55 nm (D-), anisometric particles of lengths within ~100-160 (L-) and ~85-125 nm (D-), and widths within ~10-20 (L-) and ~20-30 nm (D-).

Acute Pancreatitis Secondary to Cocaine Intoxication: A Case Series.

Gallstones, alcohol use, hypertriglyceridemia, and hypercalcemia have been considered the most common causes of acute pancreatitis; however, about 20% of the cases remain idiopathic since no definite cause can be established. It has been noticed that there is a small number of patients who have presented to the hospital with a diagnosis of acute pancreatitis who have concurrently been using cocaine yet have no recent alcohol use and no gallstones. The purpose of this series of case reports is to review the evidence behind the association between cocaine and pancreatitis.

Effect of Selenium and Garlic Extract Treatments of Seed-Addressed Lettuce Plants on Biofortification Level, Seed Productivity and Mature Plant Yield and Quality.

The enhancement of the plant seed yield and quality represents the basis of the successful productivity of the deriving crop. The effect of single and combined foliar treatments of lettuce plants with sodium selenate and garlic bulb extract on seed yield and quality and on mature plant biochemical characteristics was investigated using four lettuce cultivars (Bouquet, Picnic, Moskovsky parnikovy and Cavalier). The seed production of plants treated with Se increased by 20-41%, compared to the untreated control plants, while the augmentation was as much as 10-23% and 17-27% under garlic extract and the joint application of Se and garlic, respectively.

Atypical Manifestation of Adult Polycystic Kidney Disease in an Elderly Individual.

Autosomal dominant polycystic kidney disease (ADPKD) is a rare genetic disease. Diagnosis of ADPKD is usually made by the number of renal cysts on the ultrasound for each age category. There are two types of ADPKD, and the patients with the second type have later onset of symptoms, with slower disease progression than in the first type.

Massive Calcified Abdominal Aortic Aneurysm Presenting as Low Back Pain.

Calcified abdominal aortic aneurysm (CAAA) is a radiological finding that manifests the calcification in the bulged aortic walls. CAAA has high mortality. The presence of calcification as a key player in abdominal aortic aneurysm (AAA) rupture risk was reported in the literature.

Metastatic Clear Cell Renal Cell Carcinoma Presenting as Acute Appendicitis.

Renal cell carcinoma (RCC) is a malignant tumor arising from the epithelial cells of kidney tubules. It may metastasize to many sites; however, metastasis of RCC to the appendix is very rare. Renal cell carcinomas usually metastasize to the lungs, lymph nodes, bones, or liver.

Unexpected clinical case of infectious endocarditis in a patient with iv drug abuse: why epidemiological history matters.

Introduction: Right-sided lesions caused by staphylococci are the most common clinical entity of infectious endocarditis (IE) among iv drug abusers. But some aspects of the epidemiological history are critical in terms of early detection of uncommon pathogens.

Case Report: We describe a clinical observation of native aortic valve IE caused by in a 37-year-old female with a history of heroin addiction, alcohol abuse and liver cirrhosis.

Speckle-Based Sensing of Microscopic Dynamics in Expanding Polymer Foams: Application of the Stacked Speckle History Technique.

Microscopic structural rearrangements in expanding polylactide foams were probed using multiple dynamic scattering of laser radiation in the foam volume. Formation and subsequent expansion of polylactide foams was provided by a rapid or slow depressurization of the "plasticized polylactide-supercritical carbon dioxide" system. Dynamic speckles induced by a multiple scattering of laser radiation in the expanding foam were analyzed using the stacked speckle history technique, which is based on a joint mapping of spatial-temporal dynamics of evolving speckle patterns.

[CLINICAL AND PSHYSIOLOGICAL FEATURES OF INTRAOSSEOUS ANESTHESIA DURING DENTAL IMPLANTATION].

The aim of research - to assess the feasibility and effectiveness, of the intraosseous method of anesthesia, with the Quick Sleeper injection system on the toothless area of ​​the alveolar bone during dental implantation. Clinical and physiological studies were conducted to study the features of performing intraosseous anesthesia on the site of alveolar bone adentia in the absence of the usual anatomical topographic landmarks. New computer technologies, as well as modern methods of patient examination and observation were used.

Extreme Foaming Modes for SCF-Plasticized Polylactides: Quasi-Adiabatic and Quasi-Isothermal Foam Expansion.

The experimental evidence on depressurization foaming of the amorphous D,L-polylactide, which is plasticized by subcritical (initial pressures below the critical value) or supercritical (initial pressures above the critical value) carbon dioxide at a temperature above the critical value, relates to two extreme cases: a slow quasi-isothermal foam expansion, and a rapid quasi-adiabatic expansion. Under certain conditions, the quasi-isothermal mode is characterized by the non-monotonic dependencies of the foam volume on the external pressure that are associated with the expansion-to-shrinkage transition. The quasi-adiabatic and quasi-isothermal expansions are characterized by a significant increase in the degree of foam expansion under conditions where the CO initial pressure approaches the critical value.

Evaluation of Allergenic, Immunogenic, and Skin-Irritant Effects of Deicing Chemicals in Warm-Blooded Animals.

We studied allergenic, immunogenic, and skin-irritating effects of deicing chemicals HCM (Volgograd), Bishofit (Turkmenia), and Nordix-P (Russia) in model experiments on various types of laboratory animals (rats, mice, rabbits). All the studied deicing chemicals exhibited weak immunotoxic activity and in high doses can cause delayed-type hypersensitivity reaction that manifested in skin irritant effect on the skin and produced a suppressive effect on the humoral immunity. The modified method for assessing skin irritation proposed by us is more sensitive than standard methods.

[Legal aspects of examination concerning complicated cases of occupation connection with disease].

The article deals with problems arising in consideration of relations between disease and occupation. The authors presented and analyzed legal occupational therapy documents that regulate examination for connection between disease and occupational activities. Consideration also covers legal aspects and solutions of debates in complicated examination cases with specific clinical examples of legal expertise, based on experience of FGBNU VSIMEI personnel.

[SCIENTIFIC EVIDENCE FOR HYGIENIC STANDARDS HARMONIZED WITH INTERNATIONAL RECOMMENDATIONS FOR PRIORITY POLLUITIONS OF SOILS].

In accordance with international approaches the ranking of permissible levels of chemicals in the soil for the Russian Federation was performed with the use of actual maximum permissible concentration (MPC), there were scientifically substantiated 33 standardsfor 26 substances and their combinations in the soil, differentiatedfor 6 groups offunctional areas for soil use. There is presented the algorithm determining the procedure for the establishment of MPC for unstudied chemicals for various functional areas of soil of populated areas, as well as draft of amendments to existing sanitary-hygienic regulations prior to processing the latter in accordance with modern requirements.

[The impact of the long-term exposure of industrial aerosols on clinical and functional indices of the broncho-pulmonary system in aluminum smelter workers].

It was found that the appearance of respiratory diseases among workers was established to be associated with the impact of aerosols with the complex chemical composition, exceeding corresponding MAC. Among respiratory diseases in workers there were detected predominantly chronic non-obstructive bronchitis - 59.15%, and chronic obstructive pulmonary disease (COPD) - in 35.

[Methodological aspects of the assessment of phytotoxicic properties of ice-melter reagents].

One of the main criteria which determine the possibility of the use of a particular type of ice-melter reagents (IMR) is the degree of their safety for the environment and human health, which is reflected in the establishment of safe doses and concentrations. In this regard, the current area of research is to improve the ecological and epidemiological principles of risk assessment of modern types of anti-icing agents. Currently available data concerning monitoring soil studies and the snow held in various cities of Russia, show that there is a process of accumulation of the main components of IMR - sodium and chlorine ions in the areas related to the roadway.

[Cryoglobulinemia in a case of multiple myeloma associated with viral hepatitis B].

Cryoglobulinemia is a biochemical disorder accompanying many infectious, systemic, and lymphoproliferative conditions. Cryoglobulins are proteins capable of reversible precipitation or gel formation at temperatures below 37 degrees C. There are 3 types of cryoglobulins depending on the type of immunoglobulins in their composition; hence, three types of cryoglobulinemia occurring in different diseases.

Laser speckle probes of relaxation dynamics in soft porous media saturated by near-critical fluids.

Speckle correlation analysis was applied to study the relaxation dynamics in soft porous media saturated by near-critical carbon dioxide. The relaxation of soft matrix deformation was caused by a stepwise change in the fluid pressure. It was found that the deformation rate in the course of relaxation and the relaxation time strongly depend on the temperature of the system.

[Regulation of safe levels of polychlorinated biphenyls in soil: Russian and international experience].

The article presents data on the levels of soil pollution by polychlorinated biphenyls (PCBs) in different regions of Russia and foreign countries. For the time present proposed regulatory value for the regulation of PCBs in soils of different land uses have been established to be set mainly on the results of the calculations of risk. However used initial values and features of the methodology for calculating determine significant variability of proposed levels of PCBs in soils.

[To a question on the impact of nanoparticles of metals present in the aquatic environment, on bacteria and continuous cell lines HEp-2 and BGM].

Promising application of nanoparticles and nanomaterials is the creation of sanitary hygienic means of new generation used for disinfection of water and indoor surfaces of mass use, furniture, sanitary technical equipment by virtue of modifying traditional materials to bring them effective biocidal properties, and for the development of methods in vitro for assessment their toxicity In this paper the possibility of the use various forms of silver, copper and aluminum as disinfectant for bacterial test organisms in the aquatic environment and assess their toxicity on biological models of continuous culture of BGM cells (a stable line of African green monkey kidney cells) and HEp-2 (Human epithelial type 2 (HEp-2) cells, derived from a human laryngeal carcinoma) is considered.

[Modern problems of development of hygienic environmental quality standards (EQS) for soil pollution].

An important step in developing measures for the management, conservation and restoration of soils contaminated with various chemicals, is a timely development of regulatory documents and their revision in the light of modern knowledge. Address issues related to the harmonization of the maximum permissible concentration (MAPC) of some chemical elements, improving the methodology of valuation methodology for the development of hygienic regulation of combinations of chemicals in the soil, as well as the improvement of computational methods study estimated allowable concentrations of chemicals of various classes of compounds and their combinations in the soil should be carried out in accordance with international requirements and trends towards integration with Europe.

Resonant scattering and absorption in the titanate-based nanoplatelet dispersions in near ultraviolet region.

Extinction enhancement and nonlinear near-resonant absorption of potassium polytitanate nanoplatelets were experimentally studied in the near-UV region. Phenomenological models such as the one-oscillator Lorentz model for dielectric function and the two-level model with the depleted ground state were used to interpret the experimental data. The introduced model parameters demonstrate the adequately high sensitivity to variations in nanoplatelet morphology and chemical environment.

Analysis of the scatter growth in dispersive media with the use of dynamic light scattering.

Analysis of the structure functions of intensity fluctuations of scattered laser light was applied to monitor the phase separation in probed disperse media. UV-cured mixtures of a liquid crystal and prepolymer were studied during the formation of the structure of dispersive polymer-liquid crystal (DPLC) composites. The experimentally observed features of light beating induced by dynamic light scattering in DPLC systems (the scaling properties of the structure functions, the narrowing of the beating spectrum for certain weight fractions of the liquid-crystalline component) were interpreted in terms of the discrete scattering model using the results of statistical modeling.

[Skin resorptive effect of petroleum on some biochemical and immunological parameters in experimental animals].

Petroleum and its transformation products accumulated in soil along multiple trophic chains enter the human body, which increases the risk of environmentally induced diseases. A thirty-day experiment studied the cutaneous effect of different doses (4250, 850, and 425 mg/kg) of sunflower oil-emulsified petroleum. Its sensitizing and allergic effects were studied on albino guinea pigs.

[Topical problems of occupational allergic diseases nowadays].

The article covers materials on occupational allergic diseases prevalence in variable economic branches of Baikal area, if compared to the values in Russian Federation in general. The authors defined major etiologic factors resulting in allergic diseases, demonstrated that immune suppression is a major concept in occupational skin and respiratory system diseases, revealed immune response peculiarities in accordance with acting occupational allergen type.

Comparison of biphasic insulin aspart 30 given three times daily or twice daily in combination with metformin versus oral antidiabetic drugs alone in patients with poorly controlled type 2 diabetes: a 16-week, randomized, open-label, parallel-group trial conducted in russia.

Background: Modern premixed insulins offer a flexible approach to the initiation of insulin therapy in patients with poorly controlled type 2 diabetes. A disadvantage of twice-daily regimens of biphasic insulin aspart 30 (BIAsp 30) is that lunchtime control (when no insulin is administered) can be suboptimal. Therefore, it is possible that administering BIAsp 30 thrice daily might further optimize glycemic control and offer an option for patients in whom metformin (MET) is contraindicated.