Anastomotic leak: genetic aspects of prediction and choice of surgical treatment tactics.

Objective: Aim: To improve the treatment results of patients with anastomotic leaks by studying genetic predisposition.

Patients And Methods: Materials and Methods: The object of this prospective study were 17 patients with anastomotic leaks. A group of 80 practically healthy people was tested as control.

Laparoscopic cecal pole resection for LAMN a case report.

Introduction And Importance: Low-grade appendicular mucinous neoplasms are rare. In contrast to other malignant tumors, they lack the ability for infiltrative growth or lymph node metastasis, but intraperitoneal mucin spread may lead to a life-threatening condition, known as a pseudomyxoma peritonei.

Case Presentation: Patient, a 47-year-old female, with complaints of a palpable mass in her right inguinal area, presented to our clinic.

Disseminated peritoneal leiomyomatosis after laparoscopic myomectomy - A case report.

Introduction And Importance: Disseminated peritoneal leiomyomatosis (DPL) is a rare benign disease, characterized by intraperitoneal dissemination of smooth-muscle tumor masses.

Case Presentation: The patient, a 40-year-old, female - presented with complaints of periodic back pain. During the initial workup, a tumor mass was visualized in the pelvis on ultrasound.

Successful Endoscopic Treatment of a Pancreatic Pseudocyst in a Patient with Situs Inversus Totalis and Upper GI Duplication.

BACKGROUND Duplication of the gastrointestinal tract is a rare congenital malformation that can develop in any part of the digestive tract. These duplications may be asymptomatic into adult age. Situs inversus totalis is a rare congenital anomaly characterized by a mirror transposition of thoracic and abdominal organs.

Surgical treatment of a cystic neoplasm of the posterior mediastinum: Case report and literature review.

Introduction And Importance: The study presents a clinical case of removal of a paravertebral tumour by thoracoscopic method and a review of the literature on the diagnosis and treatment of posterior mediastinal tumours.

Case Presentation: A 26-year-old female patient presented with an extradural, paravertebral posterior mediastinal tumour and complaints of low back pain. The mass was diagnosed by computer tomography (CT) and magnetic resonance imaging (MRI).

Duodenum-preserving pancreatic head resection or pancreatoduodenectomy for the surgical treatment of paraduodenal pancreatitis: a retrospective cohort study.

Purpose: Paraduodenal pancreatitis (PDP) is an uncommon yet well-described type of focal chronic pancreatitis. The aim of our study was to compare the outcomes of surgical treatment of patients with PDP using pancreatoduodenectomy and duodenum-preserving pancreatic head resection (DPPHR).

Methods: A retrospective analysis of 153 consecutive patients with PDP was performed.

EVALUATION OF RESULTS OF ERAS PROGRAM AFTER PANCREATODUODENECTOMY DEPENDING ON THE TYPE OF GASTROINTESTINAL RECONSTRUCTION.

Objective: The aim: To assess the effect of gastrojejunostomy with Braun anastomosis during PD for prevention of DGE in ERAS protocol patients.

Patients And Methods: Materials and methods: A total of 92 patients from 28 to 75 years were included in this study, who underwent PD with ERAS program. Patients were divided into 2 groups, depending on type of reconstruction - PD with Child reconstruction and PD with gastrojejunostomy with Braun anastomosis.

Lung metastasis after pneumonectomy: Is there a place for surgery?

Resection of the contralateral lung after primary total pneumonectomy is a real surgical option for patients with secondary lung disease.

ANALYSIS OF POLYMORPHISM OF MATRIX METALLOPROTEINASE-2 (C-1306 → T) AND TISSUE INHIBITORS OF METALLOPROTEINASE-2 (G303 → A) GENES IN PATIENTS WITH ANASTOMOTIC LEAK IN HOLLOW DIGESTIVE ORGANS.

To analyze the frequency of polymorphic variants of MMP-2 (C-1306 → T) and TIMP-2 (G303 → A) genes in patients with anastomotic leak in hollow digestive organs. The object of the study comprises 61 patients with anastomotic leak and connective tissue pathology, all treated at the Shalimov National Institute of Surgery and Transplantology during 2016-2019. Laboratory, genetic, histological studies and statistical analysis were performed.

[Not Available].

Incidence of cancer recti (CR)in Ukraine constitutes 38 in 100 thousands of population. There are two main trends in surgical treatment of precancerous states and early stage CR: radical rectal resection and local transanal excision of the affection zone. After a single—port procedure introduction into laparoscopic surgery the alternative method of rectal tumors resection have had evolved — a transanal minimally invasive surgery with single—port (TAMIS).

Upper Bounds on Spontaneous Wave-Function Collapse Models Using Millikelvin-Cooled Nanocantilevers.

Collapse models predict a tiny violation of energy conservation, as a consequence of the spontaneous collapse of the wave function. This property allows us to set experimental bounds on their parameters. We consider an ultrasoft magnetically tipped nanocantilever cooled to millikelvin temperature.

[COMBINATION OF CELLS TECHNOLOGIES AND MINSIINVASIVE SURGERY IN THE TREATMENT OF CHRONIC GASTRIC ULCER].

The results of experimental and clinical use of stimulants of local reparative processes (autologous purified lipoaspirate and platelet-rich plasma) in the treatment of chronic gastric ulcer were analyzed. In the experimental part of the study the benefits of using platelet-rich plasma as donator growth factors were proved. The ability to stimulate the activity of fibroblasts and vessels formation in the young connective tissue with improving of oxygenation in ulcers and enhancing of cell proliferation, differentiation and accelerating of connective tissue maturation and healing of ulcers were demonstrated.

[MORPHOLOGICAL PECULIARITIES OF MUSCULO-APONEUROTIC TISSUES OF ANTERIOR ABDOMINAL WALL IN PATIENTS, SUFFERING MORBID OBESITY].

Results of morphological investigation of musculo-aponeurotic structures of anterior abdominal wall were presented in the morbid obesity patients. The role of obesity as a primary cause for morphofunctional insufficience of musculo-aponeurotic structures was established.

[ЕXPERIMENTAL ESTIMATION OF THE LOCAL APPLICATION EFFICACY OF BIOLOGICAL STIMULATOR FOR THE SOFT TISSUES REPARATION IN TREATMENT OF CHRONIC GASTRIC ULCERS].

Results of experimental investigation for studying of the local application possibility for the reparative processes stimulators, including autologic purified lipoaspirate, dalargin and a platelet—rich plasma (PRP) for treatment of chronic gastric ulcers, were analyzed. The advantages of PRP application, as the growth factors donator, independently and in combination with dalargin, were proved. The PRP capacity to stimulate the fibroblasts activity and creation of vessels in young connective tissue was proved, what have leaded to the ulcer tissues oxygenation improvement and cellular proliferation promotion, acceleration of the connective tissue maturation, and the ulcer healing.

[MORPHOLOGICAL AND IMMUNOPHENOTYPE OF DESCRIPTION OF LIPOASPIRATE CELLS].

In an experimental investigation immunophenotype and morphological characteristics of cells isolated from adipose tissue were studied. It is establised that cells derived from lipoaspirate, namely the third subpopulation cells, characterized by the features inherent to mesenchymal stem cells (SC) and SC similar to those of bone marrow. The presence of cells isolated from lipoaspirate, features that characterize them as the SC, is the perspective of their use in clinical practice.

[SURGICAL TACTICS IN CHRONIC PANCREATITIS WITH SIGNS OF BILIARY HYPERTENSION].

The results of treatment of 84 patients for chronic pancreatitis with the biliary hypertension signs were depicted. In 83 patients operative interventions were performed, and in 1--positive results were achieved after pancreatic cyst puncture under ultrasonographic control. In 51 patients the conduction of Frey operation have permitted to achieve a lower pressure inside biliary system, in 25--the additional procedures were applied for a biliary hypertension elimination.

[MODERN METHODS OF PROGNOSTICATION OF THE RECURRENCES OCCURRENCE AFTER SURGICAL TREATMENT OF THE MAMMARY GLAND BENIGN TUMORS].

Modern schemes of the recurrences predicting after surgical treatment of benign tumors of mammary gland (BTMG) were estimated. In accordance to data of retrospective investigation obtained, the recurrences occurrence rate through a five-year period of observation have constituted 2.3%.

[Peculiarities of heterotopic transplantation of adipose graft enriched by allogeneic cryopreserved stem cells from adipose lipoaspirate].

Possibilities of application of the donor cryoconserved cellular material (mesenchymal stem cells, obtained from adipose tissue) for defense of transplanted adipose graft from the tissue resorption were studied. The adipose graft enrichment, using cryoconserved allogenic mesenchymal multipotent stem cells, obtained from adipose tissue, caused activation of destructive-inflammatory processes in adipose graft, the adipocytes survival worsening, and in further--the transplant mass deficiency. We suggest inexpedient to apply in clinical practice the donor cryoconserved stem cells for defense of transplanted adipose tissue from the tissue resorption.

[Classification of an acute pancreatitis: revision by international consensus in 2012 of classification, adopted in Atlanta].

In 1992 on symposium in Atlanta the general classification of an acute pancreatitis, adopted by world medical society for practical application, was proposed. Due to results of multiple investigations there were enhanced the data about an acute pancreatitis pathophysiology, the organs insufficiency, and improvement of the noninvasive and invasive methods of visualization and treatment, what caused necessity to revise the classification. Web-consultations were conducted in 2007 yr to guarantee a wide participation of pancreatologists.

[Surgical treatment of patients for abdominal sepsis].

Results of surgical treatment of 201 patients, suffering abdominal sepsis (AS), which have occurred after operations on abdominal organs, were analyzed. Expediency of application of modern scales for the patients state severity estimation, prognostic sign-posts and dynamic of the pathological process course in every patient was substantiated. Existing systems of prognostication (APACHE II, SOFA, MODS) are applied restrictedly for diagnosis of infection in patients, what demands relaparotomy performance in presence of clinical signs of intraabdominal infection, which persists.

Atomic resolution scanning tunneling microscopy in a cryogen free dilution refrigerator at 15 mK.

Pulse tube refrigerators are becoming more common, because they are cost efficient and demand less handling than conventional (wet) refrigerators. However, a downside of a pulse tube system is the vibration level at the cold-head, which is in most designs several micrometers. We implemented vibration isolation techniques which significantly reduced vibration levels at the experiment.