The Impact of Parasitic Infestation on Nutritional Status and Micronutrients among Children.

Background: Micronutrient deficiency is a great problem that is augmented by infection and poor nutrition. Iron, zinc, and selenium are trace elements needed for human growth.

Objective: To investigate the impact of parasitic infection on nutritional status and serum iron, zinc, and selenium in children attending Pediatrics Outpatient Clinic of Zagazig University Hospitals.

Could Bordetella pertussis vaccine protect against coronavirus COVID-19?

According to the World Health Organization (WHO), as of today, there are 2.165.500 confirmed cases of the novel coronavirus disease (COVID-19) and 145.

Vascular endothelial growth factor and pulmonary hypertension in children with beta thalassemia major.

Objective: The purpose of this study was to illustrate the association between vascular endothelial growth factor level and pulmonary artery hypertension in children with β-thalassemia major.

Method: This case-control study was conducted on 116 children with β-thalassemia major; 58 of them had pulmonary artery hypertension. They were compared to 58 healthy children who were age and sex-matched (control group).

B adrenergic receptor gene polymorphism effect on childhood asthma severity and response to treatment.

BackgroundAlterations of B2 adrenergic receptor (βAR) can modulate the severity of asthma and the response to treatment. Therefore, we aimed to evaluate βAR gene polymorphism at codons 16 and 27 and their effect on asthma severity and response to treatment in asthmatic children.MethodsCase-control study was conducted on 156 children; 104 of them had bronchial asthma and 52 were healthy children (control group).

Trace elements and oxidative stress in children with type 1 diabetes mellitus.

Background: The early imbalances of trace elements in type 1 diabetes (T1D) may cause disturbance of glucose metabolism and more oxidative stress that may enhance the development of insulin resistance and diabetic complications. We aim to evaluate the serum level of selenium (Se), zinc (Zn), magnesium (Mg), and copper (Cu), the degree of oxidative stress and evaluate their relations to glycemic control in children with T1D.

Methods: A case-control study which included 100 diabetic children and 40 healthy children age, sex, and ethnicity-matched as a control group.

The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes.

Objective: The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes.

Method: This case-control study was conducted on 72 children with type 1 diabetes and compared to 48 healthy children, who were age, sex, and ethnicity-matched. The diabetic children were divided according to their glycosylated hemoglobin (A1c %) into two groups: poor and good glycemic control groups.

Angiotensin-converting enzyme insertion/deletion gene polymorphism in Egyptian children with CAP: A case-control study.

Background: Community-acquired pneumonia (CAP) is a major cause of childhood morbidity and mortality worldwide. The angiotensin-converting enzyme (ACE) gene is a potential candidate gene for CAP risk.

Objectives: In this study, we aimed to investigate whether the ACE insertion/deletion (I/D) polymorphism (rs4340) could be a genetic marker for CAP susceptibility in Egyptian children, and we also measured the serum ACE level to assess its relation to such polymorphism.

Effectiveness and impact of rotavirus vaccines in Saudi Arabia: A single hospital-based study.

Background And Study Aims: Rotavirus is the most important cause of severe gastroenteritis in children. The primary public health intervention is vaccination. Rota vaccine has been included to the national vaccination schedule in Saudi Arabia since 1 January 2013.

Early predictors of brain damage in full-term newborns with hypoxic ischemic encephalopathy.

Objective Of The Study: To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE).

Patients And Methods: A case-control study including 25 full-term new-born infants with perinatal asphyxia who were admitted to neonatal intensive care unit (NICU) with a proven diagnosis of HIE, compared to 20 healthy age- and sex-matched full-term newborns. All newborn infants were subjected to full history taking, clinical examination, routine investigations (cord blood gases and complete blood picture), and assessment of serum CK-BB (cord blood, 6 and 24 hours after birth) and urinary L/C ratio (collected within the first 6 hours, on the 2nd and 3rd day after birth).

The role of serum apelin in retinopathy of prematurity.

Objective: To evaluate the role of serum apelin as a diagnostic tool in retinopathy of prematurity (ROP) disease.

Patients And Methods: Thirty-eight preterm infants (60% male) with gestational age ranging from 30 to 36 weeks admitted to the neonatal intensive care unit, KJO Hospital, Saudi Arabia with proven diagnosis of ROP were included in the study. In addition, 27 preterm infants without ROP served as controls.

Assessment of left ventricular mass index could predict metabolic syndrome in obese children.

Background: Childhood obesity is a major risk factor for cardiovascular diseases in children and adults.

Objectives: The purpose of this study was to evaluate the serum leptin level and the cardiac changes in normotensive obese children and to study the relationship between left ventricular mass index (LVMI) and serum leptin with the parameters of metabolic syndrome (MS) in obese children.

Methods: This study was conducted in al Jeddani Hospital and Ibn Sina College Hospital in Saudi Arabia in the period from July 2012 to December 2013, and included 82 obese children.