Publications by authors named "Usama M Ali"

Background: Several studies report increases in the incidences of primary central nervous system (CNS) tumors. The reasons for this are unclear.

Methods: Data on all 188 340 individuals diagnosed with a primary CNS tumor in England (1993-2017) were obtained from the National Cancer Registration and Analysis Service.

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Article Synopsis
  • Glioblastoma is a deadly brain tumor that typically requires aggressive treatment, including surgery and chemotherapy, especially challenging for older patients who face increased risks and shorter survival times.
  • The study aimed to identify the most effective and safe treatment methods for elderly patients (aged 65 or 70+) with newly diagnosed glioblastoma, while also evaluating the associated costs and resource utilization.
  • After reviewing numerous clinical trials, 12 randomized studies were included, focusing specifically on older adults with glioblastoma, highlighting the varying definitions of "elderly" and indicating most participants were capable of self-care.
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