This report presents the case of a seven-year-old child diagnosed with Grisel's syndrome following a craniotomy for a cystic brain lesion. The patient initially presented with persistent, progressively worsening headaches that coincided with neurological symptoms. Imaging revealed a massive cystic lesion causing a significant compression and midline shift.
View Article and Find Full Text PDFBackground & Aims: Treatment options for moderate to severe ulcerative colitis (UC) are increasing rapidly, but the lack of comparative efficacy trials makes treatment choices a clinical challenge. This network-meta-analysis aimed to compare the relative efficacy of biologics and small molecules in achieving remission in patients with moderate to severe UC.
Methods: The literature was searched up to May 2024.
Objective: Aneurysmal bone cysts (ABCs) are benign but aggressive vascular lesions within bone. Orbital ABCs, though rare, are clinically significant due to the risk of debilitating symptoms such as vision loss.
Methods: Our systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using PubMed, Google Scholar, Embase, and SCOPUS databases to identify and assess primary articles exploring orbital ABC cases.
Background: The impact of biologic therapies on body mass index (BMI) in patients with inflammatory bowel disease (IBD) is unclear. This study investigates any associations between BMI, type of IBD, and the type of medications taken among patients with IBD with varying weight categories.
Methods: A cross sectional study was performed in an IBD tertiary care center.
The wildfire-like spread of COVID-19, caused by severe acute respiratory syndrome-associated coronavirus-2, has resulted in a pandemic that has put unprecedented stress on the world's healthcare systems and caused varying severities of socio-economic damage. As there are no specific treatments to combat the virus, current approaches to overcome the crisis have mainly revolved around vaccination efforts, preventing human-to-human transmission through enforcement of lockdowns and repurposing of drugs. To efficiently facilitate the measures implemented by governments, rapid and accurate diagnosis of the disease is vital.
View Article and Find Full Text PDFIntroduction: Few data exist regarding the immunogenicity of the third dose of BNT162b2 relative to the second dose in patients with inflammatory bowel disease (IBD) on different immunosuppressive therapies. We investigated the immunogenicity of BNT162b2 vaccine booster dose in patients with IBD on infliximab combination therapy.
Method: This is a prospective single-center observational study conducted from January 1, 2022 to February 28, 2022.
Objective: This paper investigates the relationship between the positivity rate and numbers of deaths and intensive care unit (ICU) patients. In addition, it explores the use of the positivity rate as an indicator for the spread of COVID-19.
Methods: We used COVID-19 datasets for eight countries - Canada, USA, UK, Italy, Belgium, Ireland, Colombia and South Africa - and considered two correlation cases.