The World's First Implantation of a Personalized Microporous Titanium Sternum with Motile Costal Clip Connections: A Case Report.

Extensive chest wall defects occur in 28% of all sternal resection cases and are a major challenge in thoracic surgery. These cases are generally considered "critical defects" requiring primary or secondary reconstruction using various types of flaps, mesh repairs, bone autografts, or endoprosthesis. The past decade witnessed rapid advances in the application of personalized endoprostheses in thoracic surgery.

Novel Immortalized Human Multipotent Mesenchymal Stromal Cell Line for Studying Hormonal Signaling.

Multipotent mesenchymal stromal cells (MSCs) integrate hormone and neuromediator signaling to coordinate tissue homeostasis, tissue renewal and regeneration. To facilitate the investigation of MSC biology, stable immortalized cell lines are created (e.g.

[The application of computed stabilometry for the diagnostics of vestibular disorders following stapedoplasty and for the estimation of the functional status in man].

The present work was designed to estimate changes in the quality of the equilibrium function (QEF) and dynamic stabilization indices (DSI) of the vertical position of the body in comparison with the traditional stabilometric characteristics (the length and the area of statokinesigram, mean radius of body deviation, average linear centre of foot pressure displacement velocity). The computed stabilometric technique was used to study the equilibrium function in the patients (n=133) presenting with otorhinolaryngological problems and requiring the surgical treatment. It was shown that selected stabilometric characteristics (such as QEF and DSI) may be useful for control of the efficacy of the treatment of surgical patients; moreover, they can be applied to the evaluation of dynamics of the patients' health status during the postoperative period.

[The stabilometric evaluation of resistance to motion sickness in man].

This work was designed to develop a mathematical model based on the results of computed stabilometry in the subjects differing in the degree of resistance to motion sickness. The model is designed for the purpose of instant diagnostics in the course of occupational selection. Stabilometric characteristics of 61 men aged from18 to 24 years were compared with those obtained by the method of continuous cumulation of Coriolis accelerations.

[The CT-guided transthoracic biopsy of lung's and mediastinal tumors].

The results of 107 CT-guided transthoracic biopsies, conducted during 2005-2010 yy, were analyzed. The authors have shown the advantages of the core biopsy compared with the fine-needle aspiration biopsy (FNAB). Sensitivity of the first for the malignant tumors was 93%, while the FNAB sensitivity was only 75%.

[Physiological nature and diagnostic implications of rotational nystagmus].

The authors provide a rationale for clinical studies of four types of rotational nystagmus, true vestibular, cervico-vestibular, opto-vestibular, and cervico-optovestibular. A physiological concept of nystagmus during active head rotation is formulated. Negative consequences of vestibular nystagmus as a pathophysiological reaction are discussed.

[New methodology for the stabilometric diagnosis of equilibrium dysfunction].

The necessity of studying the dynamic stabilization of the human body vertical position is substantiated. New capacities of a stabilometric vector analysis in diagnosing equilibrium dysfunction, evaluating the efficiency of treatment, and determining the statistical significance of differences in the results in a patient rather than in a group of subjects are shown.

[Circulation of West Nile virus (Flaviviridae, Flavivirus) and some other arboviruses in the ecosystems of Volga delta, Volga-Akhtuba flood-lands and adjoining arid regions (2000-2002)].

Comprehensive virological, serological as well as genetic studies of the ecology of West Nile Virus (WNV) as well as of some other arboviruses were undertaken in different ecosystems in the territories of the Astrakhan Region and of the Kalmyk Republic. The main carriers (mosquitoes, ticks, birds and mammals) were defined as involved in the circulation of viruses within the natural and anthropogenic biocenosis. Phylogenetic examinations of isolated strains and samples, which were positive in RT-PCR, showed an absolute predominance of genotype I virus that was most closely related to American and Israeli strains.

West Nile virus and other zoonotic viruses in Russia: examples of emerging-reemerging situations.

Studies of the interactions of vertebrates, viruses and arthropod vectors of these viruses were monitored in terms of different ecological groups of viruses transmitted by mosquitoes and ticks in Northern Eurasia in an area encompassing more than 15 million km2. About 90 viruses were isolated, including 24 new to science. Newly recognized infections of vertebrates, including humans, were described.

[Therapy of primary open-angle glaucoma by oftan-dipivefrin].

Choice of optimal hypotensive therapy with the minimal side effects remains a serious problem in therapy of glaucoma. The efficacy and safety of oftan-dipivefrin (Sante, Finland) and glaucon (Alcon, USA) are compared in a controlled balanced randomized open parallel study preceded by a period for discharge of the previous drugs. The period of discharge was 7 days, active treatment was administered for 8 weeks.

Interaction between the vestibular, optical, and proprioceptive sensory systems during realization of rotary nystagmus.

Questions related to the rotary nystagmus generation in the different variants of interactions between the vestibular, optical, and proprioceptive sensory systems are considered. A physiological concept of the opto-vestibulo-cervical system is given. The biological expediency of nystagmus is considered.

[Clinical vestibulometry: current status and future prospects].

Rotation and caloric methods of vestibular stimulation proposed and adopted during the last decades have been reviewed in terms of their efficacy in differential and topic diagnosis, clinical practicability. Systemic and bio-cybernetics approaches to vestibular apparatus and function have been analyzed. The need of using neurophysiological and cybernetics methods for further progress in relevant research and most promising trends in advancing clinical vestibulometry have been determined.

[The migration of radionuclides from global fallout in the trophic chains of biogeocenoses in arid zones].

Radionuclide (137Cs and 90Sr) content in soil, plants, terrestrial vertebrates and invertebrates has been studied in Kalmyk ASSR, Turkmenian SSR, and Great Gobi Reserve (Mongolia). The content of radionuclides accumulated by wild animals in arid zone biogeocenoses and the patterns of radionuclide migration along food chains have been estimated. 90Sr was found to be involved in biological cycles with participation of soil and terrestrial organisms 3-23 times more intensively than 137Cs.

[Human reactions to prolonged centripetal accelerations (+Gz) of small magnitudes].

The effect of centripetal acceleration (+Gz) of low values (0.5-0.6 g) applied for four days against the background of relative hypokinesia was investigated.