Encapsulation of β-alanine model amino-acid in zirconium(IV) metal organic frameworks: Defect engineering to improve host guest interactions.

Metal-Organic Frameworks (MOFs) are porous coordination networks assembled through metal complexes with organic linkers. Due to their chemical versatility, these materials are being investigated for various applications including gas storage and separation, biomedicine and catalysis. The aim of this work is the encapsulation of the model β-alanine amino-acid in the nanostructured zirconium-based MOF (UiO-66) which contains the ligand HBDC (1,4-benzenedicaboxylic acid).

Ionothermal Synthesis of Cadmium Coordination Polymers: Ionic Liquid Effects on the Synthesis, Structural, and Thermal Characterization.

Ionothermal synthesis is a little used method for the preparation of coordination polymers. By this method, two cadmium compounds were synthesized, , with formula Cd(ox)F(Ina) (Ina = isonicotinate) and , Cd(NO)(4,4'-Bpy) (4,4'-Bpy = 4,4'-Bipyridine). The modification of the reaction conditions has allowed to obtain as a pure phase.

Double role of metalloporphyrins in catalytic bioinspired supramolecular metal-organic frameworks (SMOFs).

Heterogeneous catalysts are of great interest in many industrial processes for environmental reasons and, during recent years, a great effort has been devoted to obtain metal-organic frameworks (MOFs) with improved catalytic behaviour. Few supramolecular metal-organic frameworks (SMOFs) are stable under ambient conditions and those with anchored catalysts exhibit favourable properties. However, this paper presents an innovative approach that consists of using metal nodes as both structural synthons and catalysts.

Coordination and crystallization molecules: their interactions affecting the dimensionality of metalloporphyrinic SCFs.

Synthetic metalloporphyrin complexes are often used as analogues of natural systems, and they can be used for the preparation of new Solid Coordination Frameworks (SCFs). In this work, a series of six metalloporphyrinic compounds constructed from different meso substituted metalloporphyrins (phenyl, carboxyphenyl and sulfonatophenyl) have been structurally characterized by means of single crystal X-ray diffraction, IR spectroscopy and elemental analysis. The compounds were classified considering the dimensionality of the crystal array, referred just to coordination bonds, into 0D, 1D and 2D compounds.

Heterogeneous catalytic properties of unprecedented μ-O-[FeTCPP]2 dimers (H2TCPP = meso-tetra(4-carboxyphenyl)porphyrin): an unusual superhyperfine EPR structure.

During the past few years, a great deal of effort has been devoted to the anchoring of catalysts into solid coordination networks in order to achieve heterogeneous catalysts. In this sense, an innovative approach consists in using the coordination-network synthons both as structural units and as catalysts. Regarding the latter, metalloporphyrins are suitable candidates for synthons.

Fe-TPP coordination network with metalloporphyrinic neutral radicals and face-to-face and edge-to-face π-π stacking.

Compound ([FeTPPbipy](•))n (TPP = meso-tetraphenylporphyrin and bipy = 4,4'-bipyridine) is the first example of a Fe-TPP-bipy coordination network, and it consists of 1D polymers packed through face-to-face and edge-to-face π-π interactions. The compound has been investigated by means of X-ray diffraction, IR, Mössbauer, UV-visible, and EPR spectroscopies, thermogravimetry, magnetic susceptibility measurements, and quantum-mechanical density functional theory (DFT) and time-dependent DFT calculations. The chemical formula for this compound can be confusing because it is compatible with Fe(II) and TPP(2-) anions.

Thermal response, catalytic activity, and color change of the first hybrid vanadate containing Bpe guest molecules.

Four isomorphic compounds with formula [{Co2(H2O)2(Bpe)2}(V4O12)]·4H2O·Bpe, CoBpe 1; [{CoNi(H2O)2(Bpe)2}(V4O12)]·4H2O·Bpe, CoNiBpe 2; [{Co0.6Ni1.4(H2O)2(Bpe)2}(V4O12)]·4H2O·Bpe, NiCoBpe 3; and [{Ni2(H2O)2(Bpe)2}(V4O12)]·4H2O·Bpe, NiBpe 4, have been obtained by hydrothermal synthesis.

Flexible and dynamic thermal behavior of self-catenated [{Ni3(H2O)3(Bpa)4}(V6O18)]·8H2O constructed from 10-c heterometallic inorganic-organic clusters.

The hydrothermal treatment of Ni(NO(3))(2)·6H(2)O, NaVO(3), and Bpa (1,2-Di(pyridyl)ethane) (C(12)H(12)N(2)) at 120 °C during 3 days leads to green single crystals of the title compound. The single crystal X-ray diffraction reveals that [{Ni(3)(H(2)O)(3)(Bpa)(4)}(V(6)O(18))]·8H(2)O crystallizes in the monoclinic system, P2(1)/c space group, with a = 13.5536 (2), b = 19.

Defective dicubane-like tetranuclear nickel(II) cyanate and azide nanoscale magnets.

Four tetrameric nickel(II) pseudohalide complexes have been synthesized and structurally, spectroscopically, and magnetically characterized. Compounds 1-3 are isostructural and exhibit the general formula [Ni(2)(dpk·OH)(dpk·CH(3)O)(L)(H(2)O)](2)A(2)·2H(2)O, where dpk = di-2-pyridylketone; L = N(3)(-), and A = ClO(4)(-) for 1, L = NCO(-) and A = ClO(4)(-) for 2, and L = NCO(-) and A = NO(3)(-) for 3. The formula for 4 is [Ni(4)(dpk·OH)(3) (dpk·CH(3)O)(2)(NCO)](BF(4))(2)·3H(2)O.

Structural analysis, spectroscopic, and magnetic properties of the 1D triple-bridged compounds [M(dca)2(bpa)] (M = Mn, Fe, Co, Zn; dca = dicyanamide; bpa = 1,2-bis(4-pyridyl)ethane) and the 3D [Ni(dca)(bpa)2]dca·6H2O.

The family of compounds [Mn(dca)(2)(bpa)] (1), [Fe(dca)(2)(bpa)] (2), [Co(dca)(2)(bpa)] (3), [Zn(dca)(2)(bpa)] (4), and [Ni(dca)(bpa)(2)]dca·6H(2)O (5), with dca = dicyanamide and bpa = 1,2-bis(4-pyridyl)ethane, has been synthesized. These compounds have been characterized by single crystal (1, 2, 4, and 5) and powder X-ray diffraction (3), by Fourier transform infrared (FTIR), UV-vis, and electron paramagnetic resonance (EPR) spectroscopies, and by magnetic measurements. Compound 1 crystallizes in the monoclinic C2/c space group, Z = 4, with a = 16.

Tris[4,4'-(ethene-1,2-di-yl)dipyridinium] deca-vanadate dihydrate.

The asymmetric unit of the title compound, (C(12)H(12)N(2))(3)[V(10)O(28)]·2H(2)O, contains one half of a deca-vanadate anion, one and a half trans-1,2-bis-(4-pyridinio)ethene cations and one water mol-ecule. The V(10)O(28) groups are involved in a three-dimensional hydrogen-bonding network through Ow-H⋯O, N-H⋯O and C-H⋯O inter-actions.

[Evolution of the epidemiological characteristics of tuberculosis in Navarra (1994-2003)].

Aim: To describe the changes in the incidence and the epidemiological profile of tuberculosis in Navarra.

Methods: The cases of tuberculosis in the 1994-2003 period were analysed. Cases reported to the system of obligatory notifiable diseases, completed with the microbiological diagnoses and the cases collected in other health registers.

[Communicable disease surveillance in Navarre, 2004].

Epidemiological surveillance in Navarre (584,734 inhabitants) covers 34 transmissible diseases, whose notification is compulsory, and epidemic outbreaks of any aetiology. Notification is carried out on a weekly basis by the doctors from paediatrics, primary care and specialised care. In 2004, 75.

Direct, two-step synthetic pathway to novel dibenzo[a,c]phenanthridines.

Novel dibenzo[a,c]phenanthridines are prepared regioselectively by the application of a straightforward synthetic pathway, starting from new 3,4-diaryl- and 3,4-dihydro-3,4-diarylisoquinolines prepared via Ritter-type heterocyclization and the more classical two-step reductive amination/Bischler-Napieralski cyclization of triarylethanones, respectively. A comparative study of nonphenolic oxidative coupling methodologies provides a highly efficient procedure, based on the hypervalent iodine reagent phenyliodine(III) bis(trifluoroacetate) (PIFA), to accomplish the final coupling step.

[Progress in the control of HIV infection and AIDS in Navarre, 1985-2003].

The epidemiological situation of HIV infection and AIDS in Navarre in 2003 is reviewed. Up until December 2003, 1,610 HIV infections had been diagnosed in residents of Navarre, of whom 41% had died. The new diagnoses of HIV fell by some 81% between 1993 and 2003, a year in which 28 cases were diagnosed (4.

[Compulsory Diseases Notification (CDN) in Navarre 2003].

Epidemiological vigilance in Navarre covers 34 transmissible diseases, whose notification is compulsory, and epidemic outbreaks of any aetiology. Notification is carried out on a weekly basis by the doctors from paediatrics, primary and specialised level who suspect or diagnose any of these diseases. In 2003, 75.

[Epidemiological surveillance of HIV/Aids infections in Navarra between 1985 and 2002].

In the year 1985, the first cases of Aids were diagnosed in Navarra. Since then and until December 2002, according to the notifications received, 2,329 persons with HIV have been counted, of whom 1,538 were from Navarra and 791 temporary residents in this autonomous community. In recent years, the incidence of new diagnoses of HIV infection and cases of Aids has shown a clear tendency to fall in Navarra.

[State of the meningococcal disease in Navarra].

The incidence of meningococcal disease in Navarra and Spain is determined for the 1991-1997 period, with a detected density of incidence of 5.46 per 100,000 in the 1987-1991 period. In Navarra the incidence in the 1991-1997 period was of 3.

[Situation of Diseases of Compulsory Declaration (DCDs) in Navarra. 1997].

The system of Diseases of Compulsory Declaration (DCDs) encompasses, until the end of 1997, the notification of 41 transmittable infectious diseases, to which are added epidemic outbreaks of any etiology and cause. In Navarra, the DCDs are declared to the Vigilance and Epidemiological Control Section of the Public Health Institute on a weekly basis by the doctors of Primary and Specialised Care. Subsequently, the information is sent to the National Centre of Epidemiology where the data from the autonomous communities is centralised.

[Situation of Diseases of Compulsory Declaration (DCDs) in Navarra. 1998].

The System of Epidemiological Vigilance of Navarra comprises the notification of 33 transmissible infectious diseases, to which are added epidemic outbreaks of any etiology or cause. Notification to the system is carried out on a weekly basis by any doctor who suspects or diagnoses any of the processes. In our Autonomous Community, the Diseases of Compulsory Declaration (DCDs) are reported to the Section of Vigilance and Epidemiological Control of the Institute of Public Health, on a weekly basis by the doctors of Primary and Specialised Care.

[Evaluation of the Program for the Prevention and Control of Tuberculosis during the period January 1993 - June 1996].

In 1992 a Technical Commission was formed in Navarra with the participation of different specialists who drew up the Program of Vigilance and Control of Tuberculosis. We present the results of the evaluation of this program for the period from January 1993 to June 1996. In the 3.

[Surveillance report on Diseases of Compulsory Notification in Navarra. 1999].

The Epidemiological Surveillance System of Navarra includes the notification of 33 transmissible infectious diseases, to which epidemic outbreaks of any aetiology and cause are added. Reporting to the system is carried out on a weekly basis by every doctor who suspects or diagnoses any of these processes. In our autonomous community, Diseases of Compulsory Notification (DCN) are reported to the Section for the Control of Infectious Diseases and Outbreaks of the Public Health Institute on a weekly basis by the doctors of Primary and Specialised Care.

[Candidiasis secondary to antibiotic treatment in primary care].

Background: At the Pharmacological Vigilance Center of Navarra a prospective observational study was designed and promoted aimed at estimating the incidence of candidiasis and its relation with the consumption of a wide spectrum of antibiotics.

Material And Methods: The field work, which lasted for one week, was carried out with the participation of Primary Care physicians, and included all of the previously selected antibiotic treatments prescribed during that time for any pathology, a search for determinate clinical manifestations, and an evaluation of the existence of a series of predisposing factors.

Results: Of the 1,430 patients treated (by 158 family doctors in 1,098 cases adn by 29 paediatricians in 332 cases) there were 49 cases of localised candidiasis, which gives an incidence of 3.

[Surveillance report on Diseases of Compulsory Declaration (DCD) in Navarra. 2001].

The Epidemiologic Surveillance System of Navarra includes the notification of 34 communicable diseases, to which are added epidemic outbreaks of any aetiology and cause. Every doctor who suspects, or diagnoses, any of the processes carries out reporting to the system on a weekly basis. In 2001, under the heading of diseases of respiratory transmission, 7,779 cases of Flu were reported (EI: 0.