The Impact of Repetitive Transcranial Magnetic Stimulation on Functional Connectivity in Major Depressive Disorder and Bipolar Disorder Evaluated by Directed Transfer Function and Indices Based on Graph Theory.

The objective of this work was to study the impact of repetitive Transcranial Magnetic Stimulation (rTMS) on the EEG connectivity evaluated by indices based on graph theory, derived from Directed Transfer Function (DTF), in patients with major depressive disorder (MDD) or with bipolar disorder (BD). The results showed the importance of beta and gamma rhythms. The indices , and increased in MDD responders in beta and gamma bands after rTMS.

EEG Phase Synchronization in Persons With Depression Subjected to Transcranial Magnetic Stimulation.

The main objective of this work was to study the impact of repetitive Transcranial Magnetic Stimulation (rTMS) treatment on brain activity in 8 patients with major depressive disorder (MDD) and 10 patients with bipolar disorder (BP). Changes due to rTMS stimulation of the left dorsolateral prefrontal cortex (DLPFC) were investigated considering separately responders and non-responders to therapy in each of both groups. The aim of the research is to determine whether non-responders differ from responders suffered from both diseases, as well as if any change occurred due to rTMS across consecutive rTMS sessions.

Complexity Analysis of EEG Data in Persons With Depression Subjected to Transcranial Magnetic Stimulation.

The aim of this work was to study the neurophysiological effect of repetitive transcranial magnetic stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (DLPFC) in 8 patients with major depression disorder (MDD) and 10 patients with bipolar disorder (BP), considering separately responders and non-responders to rTMS therapy in each of both groups. The Higuchi's Fractal Dimension (FD) was analyzed from 64-channels EEG signals in five physiological frequency bands and every channel separately. Changes of FD were analyzed before and after 1st, 10th, and 20th session of rTMS.