Genomic Instability in Exfoliated Buccal Cells among Cement Warehouse Workers.

Background: Workers in cement warehouses of Kerala are enduring long-standing exposure to cement dust, which is considered genotoxic.

Objective: To evaluate the extent of genotoxicity and cytotoxicity caused due to exposure of cement dust among those working in cement warehouses.

Methods: The study included 82 cement warehouse workers and 82 age-matched individuals with no exposure to cement dust.

Recycling and utilization of metabolic wastes for energy production is an index of biochemical adaptation of fish under environmental pollution stress.

The activity levels of lactate dehydrogenase and lactic acid were assessed in various tissues of the fish during exposure to lethal concentration of group-II Pyrethroids (deltamethrin, cypermethrin, fenvalerate and fluvalinate) for a period of 72 hours. The results showed steady increased levels in all the tissues (blood, muscle, brain and liver) with response pattern characteristic of their own. The increased LDH activity and lactic acid levels indicate the shifting of aerobic glycolysis to anaerobiosis and its further utilization for energy production during adaptation to toxic stress.