Multicentric validation of a rapid assay for heparin-induced thrombocytopenia with different specimen types.

The diagnosis of heparin-induced thrombocytopenia type 2 (HIT) requires a combination of clinical and laboratory data. Rapid exclusion of HIT is supported by sensitive immunoassays. Citrated plasma or whole blood are more often available in the laboratory, and may thus, have practical advantages as compared to serum.