Taxonomic classification of the bacterial endosymbiont based on next-generation sequencing: is there molecular evidence for its presence in tardigrades?

We used high-throughput sequencing of 16S rRNA to test whether tardigrade species are infected with parasites. We applied SILVA and Greengenes databases that allowed taxonomic classification of bacterial sequences to OTUs. The results obtained from both databases differed considerably in the number of OTUs, and only the Greengenes database allowed identification of (infection was also supported by comparison of sequences to NCBI database).

Host-commensal interaction promotes health and lifespan in through the activation of HLH-30/TFEB-mediated autophagy.

Gut homeostasis is maintained by the close interaction between commensal intestinal microbiota and the host, affecting the most complex physiological processes, such as aging. Some commensal bacteria with the potential to promote healthy aging arise as attractive candidates for the development of pro-longevity probiotics. Here, we showed that heat-inactivated human commensal BGHV110 (BGHV110) extends the lifespan of and improves age-related physiological features, including locomotor function and lipid metabolism.