Publications by authors named "Urim Kim"

Background: Healthy aging has become increasingly important owing to the rapidly growing population of older adults globally, and results from the complex interplay of multiple characteristics such as depression and quality of life. Several countries have included peer-led interventions in their health policies to promote healthy aging. Given the growing evidence for these interventions, determining their comparative effectiveness is vital and warranted.

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This study analyzed the effects of Ca metal ions among culture medium components on the strain DSCG150 strain cell growth. The strain DSCG150 grew based on a multiple fission cell cycle and growth became stagnant in the absence of metal ions in the medium, particularly Ca. Flow cytometry and confocal microscopic image analysis results showed that in the absence of Ca, cell growth became stagnant as the cells accumulated into four autospores and could not transform into daughter cells.

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In a previous study, the sequential optimization and regulation of environmental parameters using the PhotoBiobox were demonstrated with high-throughput screening tests. In this study, we estimated changes in the biovolume-based composition of a polyculture built in vitro and composed of three algal strains: sp., sp.

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Article Synopsis
  • Algae-bacteria interactions are key contributors to harmful algal blooms (HABs), and this study aims to identify specific bacterial metabolites that influence algal growth by using a comprehensive collection of E. coli K-12 gene-disrupted mutants.
  • Screening identified 80 E. coli mutants that increased algal growth by roughly 1.5 times compared to wild-type, pinpointing five bacterial genes related to lipopolysaccharide (LPS) biosynthesis as significant factors.
  • LPS was shown to inhibit algal growth and induce oxidative stress, leading to decreased growth in various bloom-forming algae, demonstrating the effectiveness of the Keio collection method for discovering interactive bacterial metabolites and their associated genes.
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Herein, a two-stage cultivation process was devised to overcome low pigment content of algal biomass grown in heterotrophy. Post-treatment conditions (i.e.

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  • The study explored a new method to boost carotenoid production by manipulating the interaction between autophagy and carotenoid biosynthesis in Chlamydomonas reinhardtii.
  • Silencing the ATG1 and ATG8 genes using artificial microRNA significantly reduced their expression, resulting in a 2.34-fold increase in β-carotene content.
  • Additionally, the modified strains showed enhanced biodiesel properties due to higher levels of beneficial fatty acids, highlighting the potential economic benefits for algal biorefinery.
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Autophagy is a self-degradation system wherein cellular materials are recycled. Although autophagy has been extensively studied in yeast and mammalian systems, integrated stress responses in microalgae remain poorly understood. Accordingly, we carried out a comparative study on the oxidative stress responses of Chlamydomonas reinhardtii wild-type and a starchless (sta6) mutant previously shown to accumulate high lipid content under adverse conditions.

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Algal growth limitation in large-scale cultivation mostly results from high level synthesis of photosynthetic pigments, owing to self-shading effects and attenuation of light distribution. To overcome this problem, here we investigated the influence of nitrogen modulation on changes in antenna pigments as well as biomass and lipid production by Chlorella vulgaris under a chemostat continuous cultivation mode. The production of algal antenna pigments, including chlorophylls and carotenoids, was promoted in a total nitrogen (TN) concentration-dependent manner.

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