Observing the water handling in humans to resolve the role of the interstitium: preliminary results of the usability of deuterium oxide and bio-impedance analysis - a pilot analysis.

The aim of this research was to evaluate the relevance of using deuterium oxide (HO) and bio-impedance analysis (BIA) to assess size and function of the interstitium for urological research. Nineteen volunteers were recruited to this prospective trial combining ingestion of HO and BIA. Blood samples were obtained every 10 min after ingestion of HO.